Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 15/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | PRSS8 | Q16651 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6475526 | 0.94 | FAAH (0.46) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL7045498 | 0.89 | PRSS8 (0.49) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL7046962 | 0.86 | PRSS8 (0.49) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL6465889 | 0.84 | DAGLA (0.52) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL6464410 | 0.83 | FAAH (0.42) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL7046460 | 0.82 | PRSS8 (0.47) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL7049751 | 0.80 | FAAH (0.46) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL6471948 | 0.80 | CTSS (0.50) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL7575216 | 0.80 | FAAH (0.36) | FAAHCES1DAGLACYP3A4XDH | |
| SCHEMBL6467033 | 0.80 | FAAH (0.36) | FAAHCES1DAGLACYP3A4XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |