Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.35 |
| ▸ | HSF1 | Q00613 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466197 | 1.00 | FAAH (0.36) | FAAHCES1DAGLAPPARGXDH | |
| SCHEMBL7575216 | 0.94 | FAAH (0.36) | FAAHCES1DAGLAXDHLMNA | |
| SCHEMBL6467033 | 0.94 | FAAH (0.36) | FAAHCES1DAGLAXDHLMNA | |
| SCHEMBL7049041 | 0.89 | ATM (0.38) | PPARGXDHPPARDPPARACYP3A4 | |
| SCHEMBL6462134 | 0.87 | SMN1; SMN2 (0.34) | FAAHCES1DAGLAPPARGXDH | |
| SCHEMBL6465390 | 0.87 | ALDH1A1 (0.41) | FAAHCES1DAGLAPPARGTP53 | |
| SCHEMBL7045360 | 0.86 | CYP3A4 (0.38) | XDHCYP3A4 | |
| SCHEMBL6466278 | 0.85 | BMP1 (0.36) | PPARGLMNAPTPN1PTPN2PPARA | |
| SCHEMBL6468282 | 0.81 | MEN1 (0.32) | FAAHCES1DAGLASMN1; SMN2PTPN1 | |
| SCHEMBL6475526 | 0.80 | FAAH (0.46) | FAAHCES1DAGLAXDHCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161422-A1 | AMINE DERIVATIVES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055144-A1 | AMINE DERIVATIVES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |