Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3980338 | 0.87 | KCNH2 (0.39) | ALDH1A1MGLLKCNH2MAPTLMNA | |
| SCHEMBL5655348 | 0.86 | BID (0.31) | ALDH1A1MGLLMAPTHTTMEN1 | |
| SCHEMBL30240774 | 0.86 | BID (0.31) | ALDH1A1MGLLMAPTHTTMEN1 | |
| SCHEMBL5658031 | 0.82 | — | — | |
| SCHEMBL6462737 | 0.81 | NAAA (0.32) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL1276666 | 0.78 | MEN1 (0.35) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL5872296 | 0.78 | MEN1 (0.33) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL5653811 | 0.78 | MEN1 (0.33) | ALDH1A1MAPTHTTMEN1KMT2A | |
| Dymanthine SCHEMBL1276492 | 0.78 | DNM1 (0.40) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL5656345 | 0.78 | MEN1 (0.33) | ALDH1A1MAPTHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872844-B2 | Metal complexes containing acetylenic ligands, polymerization catalysts and addition polymerization process | THE DOW CHEMICAL COMPANY (US) | 2005-03-29 | — | — | US | disclosed |