Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BID | P55957 | 3/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.30 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.30 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.30 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5656345 | 1.00 | MEN1 (0.33) | MEN1MAPTHTTKMT2ANAAA | |
| SCHEMBL5872296 | 1.00 | MEN1 (0.33) | MEN1MAPTHTTKMT2ANAAA | |
| Dymanthine SCHEMBL1276492 | 0.92 | DNM1 (0.40) | MEN1MAPTHTTKMT2ANAAA | |
| SCHEMBL1276666 | 0.90 | MEN1 (0.35) | MEN1MAPTHTTKMT2ANAAA | |
| SCHEMBL6462737 | 0.87 | NAAA (0.32) | MEN1MAPTHTTKMT2ANAAA | |
| SCHEMBL30240774 | 0.86 | BID (0.31) | MEN1MAPTHTTKMT2ANAAA | |
| SCHEMBL5655348 | 0.86 | BID (0.31) | MEN1MAPTHTTKMT2ANAAA | |
| SCHEMBL29661112 | 0.83 | MEN1 (0.33) | MEN1MAPTHTTKMT2ANAAA | |
| SCHEMBL5655310 | 0.82 | MGLL (0.30) | — | |
| SCHEMBL5656636 | 0.81 | PTGS1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376406-B1 | COORDINATION POLYMERIZATION CATALYSTS FOR ALPHA-OLEFINS | THE DOW CHEMICAL COMPANY | 2002-04-23 | — | — | US | claimed |
| US-7098356-B2 | Substituted indenyl metal complexes and polymerization process | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-08-29 | — | — | US | disclosed |
| US-7074865-B2 | Azaborolyl group 4 metal complexes, catalysts and olefin polymerization process | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-07-11 | — | — | US | disclosed |
| US-20050119114-A1 | Azaborolyl group 4 metal complexes, catalysts and olefin polymerization process | DOW GLOBAL TECHNOLOGIES LLC | 2005-06-02 | — | — | US | disclosed |
| US-6872844-B2 | Metal complexes containing acetylenic ligands, polymerization catalysts and addition polymerization process | THE DOW CHEMICAL COMPANY (US) | 2005-03-29 | — | — | US | disclosed |
| US-6825295-B2 | COORDINATION POLYMERIZATION CATALYST | DOW GLOBAL TECHNOLOGIES INC. | 2004-11-30 | — | — | US | disclosed |
| US-6806327-B2 | POLYMERIZATION CATALYSTS SUCH AS (8-METHYLENE-1,8-DIHYDRODIBENZO(E,H)AZULEN-1-YL)-N-(1,1-DIMETHYLETHYL) DIMETHYLSILANAMIDE TITANIUM (II) 1,4-DIPHENYL-1,2-BUTADIENE | DOW GLOBAL TECHNOLOGIES INC. | 2004-10-19 | — | — | US | disclosed |
| US-20040010102-A1 | Bridged ylide group containning metal complexes | ROBERT BOSCH GMBH (DE) | 2004-01-15 | — | — | US | disclosed |
| US-20020183464-A1 | 3-aryl-substituted cyclopentadienyl metal complexes and polymerization process | DOW GLOBAL TECHNOLOGIES LLC | 2002-12-05 | — | — | US | disclosed |
| US-20020165329-A1 | Heat-resistant group 4 metal metallecenes having a nitrogen with aliphatic or cycloaliphatic moiety substituted with aryl group(s)and a silane bridge; high-molecular weight ethylene-alpha olefin copolymers; high concentration of comonomer | KLOSIN JERZY (US) | 2002-11-07 | — | — | US | disclosed |
| US-20020151662-A1 | Substituted polycyclic, fused ring compounds, metal complexes and polymerization process | DOW GLOBAL TECHNOLOGIES LLC | 2002-10-17 | — | — | US | disclosed |
| US-6376406-B1 | COORDINATION POLYMERIZATION CATALYSTS FOR ALPHA-OLEFINS | THE DOW CHEMICAL COMPANY | 2002-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183464-A1 | 3-aryl-substituted cyclopentadienyl metal complexes and polymerization process | SOD1, AOC3, PPOX | MEN1 4838/4885MAPT 1418/4885HTT 1764/4885 |
| US-20020165329-A1 | Heat-resistant group 4 metal metallecenes having a nitrogen with aliphatic or cycloaliphatic moiety substituted with aryl group(s)and a silane bridge; high-molecular weight ethylene-alpha olefin copolymers; high concentration of comonomer | B2M, WEE2, WASF2 | MEN1 2455/4885MAPT 2203/4885HTT 3508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.