Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6467121 | 0.87 | ALDH1A1 (0.34) | KCNH2MAPTALDH1A1MGLLSMN1; SMN2 | |
| SCHEMBL31503934 | 0.81 | HTT (0.33) | HTT | |
| SCHEMBL23647856 | 0.80 | DNM1 (0.31) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22283325 | 0.80 | DNM1 (0.31) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16715253 | 0.80 | DNM1 (0.31) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29593791 | 0.80 | DNM1 (0.31) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29970321 | 0.80 | DNM1 (0.31) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22283328 | 0.80 | DNM1 (0.31) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30767131 | 0.80 | DNM1 (0.31) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31503921 | 0.79 | ESR1 (0.38) | ALDH1A1MGLLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1299405-B1 | POLYCYCLIC, FUSED RING COMPOUNDS, METAL COMPLEXES AND POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2009-05-13 | — | — | EP | claimed |
| US-6800701-B2 | USING COORDINATION CATALYSTS | DOW GLOBAL TECHNOLOGIES INC. | 2004-10-05 | — | — | US | claimed |
| US-20030216529-A1 | Polycyclic, fused ring compounds, metal complexes and polymerization process | DOW GLOBAL TECHNOLOGIES LLC | 2003-11-20 | — | — | US | claimed |
| EP-1299405-A1 | POLYCYCLIC, FUSED RING COMPOUNDS, METAL COMPLEXES AND POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 2003-04-09 | — | — | EP | claimed |
| US-20020062011-A1 | Polycyclic, fused ring compounds, metal complexes and polymerization process | DOW GLOBAL TECHNOLOGIES LLC | 2002-05-23 | — | — | US | claimed |
| WO-2002002577-A1 | POLYCYCLIC, FUSED RING COMPOUNDS, METAL COMPLEXES AND POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGY INC. (US) | 2002-01-10 | — | — | WO | claimed |
| EP-1299405-B1 | POLYCYCLIC, FUSED RING COMPOUNDS, METAL COMPLEXES AND POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2009-05-13 | — | — | EP | disclosed |
| EP-1487886-B1 | SUBSTITUTED INDENYL METAL COMPLEXES AND POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2008-08-06 | — | — | EP | disclosed |
| US-20080051531-A1 | GAS PHASE PROCESS FOR POLYMERS WITH GROUP 4 METAL COMPLEX CATALYST ADDITION | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2008-02-28 | — | — | US | disclosed |
| EP-1497301-B1 | SUBSTITUTED POLYCYCLIC, FUSED RING METAL COMPLEXES AND POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2006-11-29 | — | — | EP | disclosed |
| US-7098356-B2 | Substituted indenyl metal complexes and polymerization process | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-08-29 | — | — | US | disclosed |
| US-6984602-B2 | Olefin polymerization catalysts containing a pyrrole bisimine ligand | UNIVATION TECHNOLOGIES, LLC (US) | 2006-01-10 | — | — | US | disclosed |
| US-6946531-B2 | Low molecular weight ethylene interpolymers and polymerization process | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-09-20 | — | — | US | disclosed |
| US-20020151662-A1 | Substituted polycyclic, fused ring compounds, metal complexes and polymerization process | DOW GLOBAL TECHNOLOGIES LLC | 2002-10-17 | — | — | US | disclosed |
| WO-2002077045-A2 | GAS PHASE PROCESS FOR POLYMERS WITH GROUP 4 METAL COMPLEX CATALYST ADDITION | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2002-10-03 | — | — | WO | disclosed |
| WO-2002074779-A1 | METAL COMPLEXES CONTAINING ACETYLENIC LIGANDS, POLYMERIZATION CATALYSTS AND ADDITION POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2002-09-26 | — | — | WO | disclosed |
| US-20020082161-A1 | Diene functionalized catalyst supports and supported catalyst compositions | THE DOW CHEMICAL COMPANY | 2002-06-27 | — | — | US | disclosed |
| US-20020062011-A1 | Polycyclic, fused ring compounds, metal complexes and polymerization process | DOW GLOBAL TECHNOLOGIES LLC | 2002-05-23 | — | — | US | disclosed |
| WO-2002002577-A1 | POLYCYCLIC, FUSED RING COMPOUNDS, METAL COMPLEXES AND POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGY INC. (US) | 2002-01-10 | — | — | WO | disclosed |
| US-20010025115-A1 | Bridged metal complexes | DOW GLOBAL TECHNOLOGIES LLC | 2001-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010025115-A1 | Bridged metal complexes | SLC39A14, NBAS, MCM4 | KCNH2 1067/4885MAPT 467/4885ALDH1A1 4718/4885 |
| US-20030216529-A1 | Polycyclic, fused ring compounds, metal complexes and polymerization process | PIN1, ZC3H18, ORC3 | KCNH2 2554/4885MAPT 979/4885ALDH1A1 3449/4885 |
| US-20020062011-A1 | Polycyclic, fused ring compounds, metal complexes and polymerization process | PIN1, ZC3H18, ORC3 | KCNH2 2554/4885MAPT 979/4885ALDH1A1 3449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.