Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.51 |
| ▸ | DAGLA | Q9Y4D2 | 5/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6475177 | 0.90 | DAGLA (0.47) | TRPV1DAGLACES1 | |
| SCHEMBL6466207 | 0.85 | DAGLA (0.46) | DAGLACES1TSHR | |
| SCHEMBL6465287 | 0.78 | TRPV1 (0.42) | TRPV1DAGLA | |
| SCHEMBL6467926 | 0.75 | DAGLA (0.44) | DAGLACES1GAA | |
| SCHEMBL7567535 | 0.71 | DAGLA (0.43) | DAGLACES1 | |
| SCHEMBL6467326 | 0.70 | FAAH (0.55) | CES1 | |
| SCHEMBL6461816 | 0.69 | DAGLA (0.42) | DAGLACES1TSHR | |
| SCHEMBL6467199 | 0.69 | DAGLA (0.41) | DAGLACES1GAA | |
| SCHEMBL5401132 | 0.64 | TRPV1 (0.51) | TRPV1 | |
| SCHEMBL2162397 | 0.63 | DAGLA (1.00) | DAGLACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |