SCHEMBL6465397

SCHEMBL6465397

NC(=O)N(c1ccc(Cc2ccc(N(C(N)=O)S(=O)(=O)c3ccc(OCc4ccccc4)cc3)cc2)cc1)S(=O)(=O)c1ccc(OCc2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA9 Q16790 2/20 0.52
CA12 O43570 1/20 0.52
CA4 P22748 1/20 0.52
CA5A P35218 1/20 0.52
CA7 P43166 1/20 0.52
CA5B Q9Y2D0 1/20 0.52
KEAP1 Q14145 1/20 0.52
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
PARP10 Q53GL7 1/20 0.49
PTPN1 P18031 1/20 0.48
PTPN12 Q05209 1/20 0.48
PTPN22 Q9Y2R2 1/20 0.48
PTGES O14684 3/20 0.48
KCNH2 Q12809 2/20 0.48
MMP2 P08253 3/20 0.47
MMP9 P14780 2/20 0.47
ADAMTS4 O75173 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6467690 0.89 KMT2A (0.51) CA1CA2CA9CA12MEN1
SCHEMBL6462883 0.86 PTGES (0.52) PTPN22PTGESALOX5
SCHEMBL6244071 0.85 KMT2A (0.57) CA1CA2CA9CA12MEN1
SCHEMBL6529186 0.82 CA1 (0.51) CA1CA2CA9CA12KMT2A
SCHEMBL8620628 0.81 TP53 (0.55) KEAP1KMT2AALDH1A1
SCHEMBL6470650 0.81 CA12 (0.50) CA1CA2CA9CA12CA7
SCHEMBL6467475 0.80 KMT2A (0.46) CA1CA2CA9CA12MEN1
SCHEMBL27679 0.77 LMNA (0.54) KEAP1MEN1KMT2AALDH1A1
SCHEMBL8837714 0.76 CA12 (0.41) CA1CA2CA9CA12CA4
SCHEMBL6466821 0.75 KMT2A (0.53) CA1CA2CA9CA12MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
EP-1480835-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
EP-1480836-A1 MIXTURE OF COLOUR DEVELOPERS Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074285-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
WO-2003074284-A1 MIXTURE OF COLOUR DEVELOPERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
EP-0792755-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-11-11 EP disclosed
EP-0792755-A1 Thermosensitive recording material OJI PAPER COMPANY LIMITED (JP) 1997-09-03 EP disclosed
US-5612280-A AROMATIC SULFONYLUREA AND SULFONYLTHIOUREA DERIVATIVES AS COLOR DEVELOPERS; COLORFASTNESS, STORAGE STABILITY, WHITENESS NEW OJI PAPER CO., LTD. (JP) 1997-03-18 US disclosed
EP-0604832-A2 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-07-06 EP disclosed