Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTAFR | P25105 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7535471 | 0.81 | CNR2 (0.36) | SMN1; SMN2ALDH1A1KMT2AMEN1CA2 | |
| SCHEMBL6467924 | 0.81 | MAPK1 (0.37) | MMP2MMP9SMN1; SMN2MAPK1MAPT | |
| SCHEMBL7047937 | 0.75 | CTSS (0.39) | — | |
| SCHEMBL6062463 | 0.75 | DAGLA (0.42) | SMN1; SMN2 | |
| SCHEMBL6467665 | 0.73 | AR (0.34) | SMN1; SMN2ALDH1A1L3MBTL1TDP1KMT2A | |
| SCHEMBL14374617 | 0.68 | PKM (0.42) | MMP2MMP9SMN1; SMN2MAPTRECQL | |
| SCHEMBL14276916 | 0.68 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPK1MAPTALDH1A1KMT2A | |
| SCHEMBL14347503 | 0.67 | SMN1; SMN2 (0.44) | MMP2MMP9SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL12139973 | 0.67 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1L3MBTL1NAMPTTDP1 | |
| SCHEMBL4948263 | 0.65 | NAMPT (0.41) | MAPTRECQLNAMPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |