Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 2/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | WDR5 | P61964 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL11184429 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTTSHRCYP3A4 | |
| Biphenyl SCHEMBL4912411 | 0.97 | LMNA (0.50) | ALDH1A1LMNAMAPTTSHRCYP3A4 | |
| Biphenyl SCHEMBL1952613 | 0.94 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTTSHRCYP3A4 | |
| Biphenyl SCHEMBL335359 | 0.94 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTTSHRCYP3A4 | |
| Biphenyl SCHEMBL473288 | 0.88 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTTSHRCYP3A4 | |
| Biphenyl SCHEMBL4593266 | 0.88 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTTSHRCYP3A4 | |
| Biphenyl SCHEMBL5143620 | 0.85 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPTTSHRCYP3A4 | |
| Biphenyl SCHEMBL28574043 | 0.83 | LMNA (0.48) | ALDH1A1LMNAMAPTTSHRCYP3A4 | |
| Urea SCHEMBL27558638 | 0.83 | MMP3 (0.68) | LMNAMAPTDHODHIKBKBMMP3 | |
| Biphenyl SCHEMBL310004 | 0.82 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTTSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6866864-B2 | Compositions and methods of use in the treatment of angiogenesis and vascular-related disorders | Mousa, Ahmed (US) | 2005-03-15 | — | — | US | disclosed |
| US-20010053356-A1 | Garlic ingredients and antioxidants in the prevention and treatment of vascular-related disorders and pathological angiogenesis-mediated disorders | MOUSA AHMED (US) | 2001-12-20 | — | — | US | disclosed |