Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | RGS12 | O14924 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24959939 | 0.77 | TDP1 (0.33) | TDP1HDAC6PPARGPPARA | |
| SCHEMBL743416 | 0.75 | TDP1 (0.32) | TDP1HDAC6 | |
| Methylamine SCHEMBL27564616 | 0.73 | NPC1 (0.38) | HTT | |
| SCHEMBL5086744 | 0.69 | MEN1 (0.41) | CES2CES1TDP1HDAC6ATM | |
| SCHEMBL28870170 | 0.68 | TDP1 (0.32) | TDP1HDAC6 | |
| SCHEMBL27886277 | 0.67 | HSD11B1 (0.33) | CES2CES1LIPG | |
| SCHEMBL647169 | 0.66 | PTGS2 (0.38) | CES2CES1PTGS2TDP1ATM | |
| SCHEMBL24959941 | 0.65 | PPARG (0.32) | TDP1PPARGPPARA | |
| SCHEMBL2274381 | 0.65 | TDP1 (0.39) | TDP1HDAC6ATMHTTHSP90AA1 | |
| SCHEMBL5084156 | 0.65 | TDP1 (0.36) | CES2CES1TDP1HDAC6ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2201047-B1 | POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW MELT ELASTICITY | CHEVRON PHILLIPS CHEMICAL CO (US) | 2016-05-04 | — | — | EP | disclosed |
| US-8637691-B2 | Polymerization catalysts for producing polymers with low melt elasticity | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2014-01-28 | — | — | US | disclosed |
| US-20130245302-A1 | POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW MELT ELASTICITY | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2013-09-19 | — | — | US | disclosed |
| US-8450437-B2 | Polymerization catalysts for producing polymers with low melt elasticity | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2013-05-28 | — | — | US | disclosed |
| US-20120108765-A1 | POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW MELT ELASTICITY | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2012-05-03 | — | — | US | disclosed |
| US-8119553-B2 | Polymerization catalysts for producing polymers with low melt elasticity | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2012-02-21 | — | — | US | disclosed |
| EP-2201047-A2 | POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW MELT ELASTICITY | Chevron Phillips Chemical Company LP (US) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009045301-A2 | POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW MELT ELASTICITY | YU YOULU (US) | 2009-04-09 | — | — | WO | disclosed |
| US-20090088543-A1 | Polymerization catalysts for producing polymers with low melt elasticity | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130245302-A1 | POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW MELT ELASTICITY | MCM4, CKAP4, MDM4 | CES2 1485/4885CES1 4275/4885PTGS2 1643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.