Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL645218 | 0.95 | CES2 (0.38) | PTGS2CES2CES1ESR1LMNA | |
| SCHEMBL743415 | 0.76 | AKT1 (0.31) | — | |
| SCHEMBL27577277 | 0.74 | ACHE (0.31) | — | |
| SCHEMBL27870084 | 0.68 | HSD11B1 (0.33) | TDP1POLB | |
| SCHEMBL28040355 | 0.67 | ESR1 (0.33) | ESR1POLB | |
| SCHEMBL28040367 | 0.67 | HSD11B1 (0.35) | POLB | |
| SCHEMBL647170 | 0.66 | CES2 (0.41) | PTGS2CES2CES1ESR1ATM | |
| SCHEMBL27717977 | 0.64 | ACHE (0.50) | PTGS2 | |
| SCHEMBL27790624 | 0.64 | ACHE (0.33) | HTT | |
| SCHEMBL27631018 | 0.63 | ACHE (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2201047-B1 | POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW MELT ELASTICITY | CHEVRON PHILLIPS CHEMICAL CO (US) | 2016-05-04 | — | — | EP | disclosed |
| US-8637691-B2 | Polymerization catalysts for producing polymers with low melt elasticity | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2014-01-28 | — | — | US | disclosed |
| US-20130245302-A1 | POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW MELT ELASTICITY | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2013-09-19 | — | — | US | disclosed |
| US-8450437-B2 | Polymerization catalysts for producing polymers with low melt elasticity | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2013-05-28 | — | — | US | disclosed |
| US-20120108765-A1 | POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW MELT ELASTICITY | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2012-05-03 | — | — | US | disclosed |
| US-8119553-B2 | Polymerization catalysts for producing polymers with low melt elasticity | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2012-02-21 | — | — | US | disclosed |
| EP-2201047-A2 | POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW MELT ELASTICITY | Chevron Phillips Chemical Company LP (US) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009045301-A2 | POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW MELT ELASTICITY | YU YOULU (US) | 2009-04-09 | — | — | WO | disclosed |
| US-20090088543-A1 | Polymerization catalysts for producing polymers with low melt elasticity | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130245302-A1 | POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW MELT ELASTICITY | MCM4, CKAP4, MDM4 | PTGS2 1643/4885CES2 1485/4885CES1 4275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.