Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463422 | 0.81 | FAAH (0.41) | KMT2AMEN1FAAHCYP3A4RAB9A | |
| SCHEMBL6207048 | 0.80 | CYP2C19 (0.48) | CYP2C19FAAHCES1 | |
| SCHEMBL7044254 | 0.75 | KMT2A (0.42) | KMT2ACYP2C19HPGDCYP3A4RAB9A | |
| SCHEMBL6467368 | 0.74 | MAOB (0.49) | KMT2AMEN1HPGDRAB9A | |
| SCHEMBL6462679 | 0.69 | FAAH (0.37) | KMT2AMEN1FAAHHPGDRAB9A | |
| SCHEMBL6463790 | 0.69 | CTSS (0.43) | FAAHCYP3A4SMN1; SMN2 | |
| SCHEMBL6461911 | 0.67 | FAAH (0.42) | KMT2AMEN1FAAHCES1SMN1; SMN2 | |
| SCHEMBL8007179 | 0.66 | KMT2A (0.67) | KMT2AMEN1CYP2C19HPGDCYP3A4 | |
| SCHEMBL24095868 | 0.65 | CES1 (0.36) | CYP2C19FAAHCES1 | |
| SCHEMBL30511427 | 0.65 | CES1 (0.36) | CYP2C19FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |