Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463655 | 0.81 | LMNA (0.39) | FAAHSMN1; SMN2CES1TAAR1NPC1 | |
| SCHEMBL6466340 | 0.81 | LMNA (0.39) | FAAHSMN1; SMN2CES1TAAR1NPC1 | |
| SCHEMBL6465748 | 0.77 | LMNA (0.40) | SMN1; SMN2NPC1RAB9ATP53KMT2A | |
| SCHEMBL7045897 | 0.75 | EPHX2 (0.38) | FAAHSMN1; SMN2HPGDEPHX2NPC1 | |
| SCHEMBL6472186 | 0.69 | KMT2A (0.38) | FAAHSMN1; SMN2HPGDCES1RAB9A | |
| SCHEMBL6468184 | 0.64 | CES1 (0.46) | FAAHHPGDCES1NCEH1 | |
| SCHEMBL7414987 | 0.64 | CES1 (0.46) | FAAHHPGDCES1NCEH1 | |
| Trifluoroacetic Acid SCHEMBL6466295 | 0.63 | CES1 (0.45) | FAAHCES1NCEH1 | |
| SCHEMBL6462292 | 0.63 | DAGLA (0.39) | FAAHSMN1; SMN2HPGDCES1NPC1 | |
| SCHEMBL6472179 | 0.61 | MMP3 (0.44) | FAAHCES1NCEH1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |