Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 4/20 | 0.33 |
| ▸ | MMP8 | P22894 | 4/20 | 0.33 |
| ▸ | MMP3 | P08254 | 2/20 | 0.33 |
| ▸ | MMP7 | P09237 | 2/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 3/20 | 0.32 |
| ▸ | MMP13 | P45452 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL648546 | 0.82 | RXRA (0.35) | SLC6A4SLC6A2PDE2AMMP9MMP8 | |
| SCHEMBL645215 | 0.80 | LMNA (0.51) | SLC6A4SLC6A2ALDH1A1MMP9MMP8 | |
| SCHEMBL646602 | 0.79 | CHRM5 (0.40) | SLC6A4SLC6A2PDE2AMMP9MMP8 | |
| SCHEMBL645639 | 0.70 | SLC6A2 (0.40) | SLC6A4SLC6A2PDE2A | |
| SCHEMBL14930469 | 0.66 | HRH2 (0.46) | KDM4ETDP1 | |
| SCHEMBL14930514 | 0.66 | HRH2 (0.46) | KDM4ETDP1 | |
| SCHEMBL8792330 | 0.66 | KCNH2 (0.42) | ALDH1A1MEN1KMT2AHCRTR1HCRTR2 | |
| SCHEMBL646801 | 0.66 | SLC6A2 (0.43) | SLC6A4SLC6A2PDE2AALDH1A1MMP9 | |
| SCHEMBL14930445 | 0.64 | ACACB (0.46) | KDM4ETDP1 | |
| SCHEMBL648828 | 0.63 | BCHE (0.51) | SLC6A4SLC6A2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119563-B2 | N-substituted azacycles | FMC CORPORATION (US) | 2012-02-21 | — | — | US | disclosed |
| US-20090215821-A1 | N-Substituted Azacycles | FMC CORPORATION | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215821-A1 | N-Substituted Azacycles | DDT, UQCRB, DNMT1 | SLC6A4 3145/4885SLC6A2 1979/4885PDE2A 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.