Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | THRA | P10827 | 5/20 | 0.51 |
| ▸ | THRB | P10828 | 5/20 | 0.51 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | RXRA | P19793 | 2/20 | 0.51 |
| ▸ | PCNA | P12004 | 2/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28641777 | 0.89 | GAA (0.53) | GAATHRATHRBPPARGPOLB | |
| SCHEMBL6473141 | 0.86 | FFAR1 (0.58) | THRATHRBPPARGPOLBHIF1A | |
| SCHEMBL1525944 | 0.84 | THRB (0.63) | GAATHRATHRBPPARGPOLB | |
| SCHEMBL1599014 | 0.83 | THRB (0.71) | GAATHRATHRBPPARGPOLB | |
| SCHEMBL6474460 | 0.79 | PPARG (0.67) | GAATHRATHRBPPARGPOLB | |
| SCHEMBL17141553 | 0.79 | TAAR5 (0.63) | GAATHRATHRBPPARGPOLB | |
| SCHEMBL30716576 | 0.79 | HPGD (0.68) | GAATHRATHRBPPARGPOLB | |
| SCHEMBL8510463 | 0.79 | HPGD (0.68) | GAATHRATHRBPPARGPOLB | |
| SCHEMBL2723833 | 0.76 | GAA (0.68) | GAATHRATHRBPPARGPOLB | |
| SCHEMBL16114045 | 0.76 | HPGD (0.68) | GAATHRATHRBPPARGPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005123099-A2 | METHODS AND COMPOSITIONS FOR ACCELERATING ALCOHOL METABOLISM | ENZYMEDIX, INC. (US) | 2005-12-29 | — | — | WO | claimed |
| US-20050271739-A1 | Methods and compositions for accelerating alcohol metabolism | ENZYMEDIX | 2005-12-08 | — | — | US | claimed |
| EP-0093653-B1 | PROCESS FOR THE PREPARATION OF IODO-THYRONINES AND IODO-THYROACETIC ACIDS BY ELECTROCHEMICAL REDUCTION AT A CONTROLLED POTENTIAL | SPIRAL Société à responsabilité limitée dite : (FR) | 1985-07-10 | — | — | EP | claimed |
| US-4490221-A | Process for preparing iodothyronines and iodothyroacetic acids by electrochemical reduction at controlled potential | SPIRAL SOCIETE A RESPONSABILITE LIMITEE DITE (FR) | 1984-12-25 | — | — | US | claimed |
| US-20200224168-A1 | COMPOSITIONS AND METHODS FOR ENHANCING MATURATION STATES OF HEALTHY AND DISEASED CARDIOMYOCYTES | UNIVERSITY OF WASHINGTON (US) | 2020-07-16 | — | — | US | disclosed |
| CN-111246863-A | Compositions and methods for enhancing the maturation state of healthy and diseased cardiomyocytes | 华盛顿大学 | 2020-06-05 | — | — | CN | disclosed |
| WO-2005123099-A2 | METHODS AND COMPOSITIONS FOR ACCELERATING ALCOHOL METABOLISM | ENZYMEDIX, INC. (US) | 2005-12-29 | — | — | WO | disclosed |
| US-20050271739-A1 | Methods and compositions for accelerating alcohol metabolism | ENZYMEDIX | 2005-12-08 | — | — | US | disclosed |
| US-6806359-B1 | HAVING BINDING AND/OR TRANSCRIPTION-ACTIVATING CHARACTERISTICS OF A GLUCOCORTICOID/MINERALCORTICOID/THYROID STIMULATING HORMONE RECEPTOR PROTEINS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES | 2004-10-19 | — | — | US | disclosed |
| US-6794160-B1 | COMPRISES PROTEINS HAVING HORMONE-BINDING AND/OR TRANSCRIPTION-ACTIVATING CHARACTERISTICS OF A GLUCOCORTICOID RECEPTOR; PLASMIDS | SALK INST FOR BIOLOGICAL STUDI (US) | 2004-09-21 | — | — | US | disclosed |
| US-5606021-A | RECOMBINANT PROTEIN WHICH HAS HORMONE BINDING AND TRANSCRIPTION ACTIVATING PROPERTIES CHARACTERISTIC OF MINERALOCORTICOID RECEPTOR | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1997-02-25 | — | — | US | disclosed |
| US-5597705-A | GENETIC ENGINEERING | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1997-01-28 | — | — | US | disclosed |
| EP-0733705-A1 | Hormone receptor compositions and methods | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1996-09-25 | — | — | EP | disclosed |
| US-5534418-A | TRANSCRIPTION IS ACTIVATED BY LIGAND COMPLEXED TO HORMONE RECEPTOR; GENETIC ENGINEERING | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1996-07-09 | — | — | US | disclosed |
| US-5312732-A | DNA and genetic engineering | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1994-05-17 | — | — | US | disclosed |
| US-5298429-A | Monitoring transcription of reporter gene | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1994-03-29 | — | — | US | disclosed |
| US-5071773-A | HORMONE RECEPTOR-RELATED BIOASSAYS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0287653-A4 | HORMONE RECEPTOR COMPOSITIONS AND METHODS. | SALK INST FOR BIOLOGICAL STUDI (US) | 1989-06-13 | — | — | EP | disclosed |
| EP-0287653-A1 | HORMONE RECEPTOR COMPOSITIONS AND METHODS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1988-10-26 | — | — | EP | disclosed |
| WO-1988003168-A1 | HORMONE RECEPTOR COMPOSITIONS AND METHODS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1988-05-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050271739-A1 | Methods and compositions for accelerating alcohol metabolism | ADH1A, ADH1C, ADH5 | GAA 1065/4885THRA 2112/4885THRB 2655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.