SCHEMBL3488959

SCHEMBL3488959

FC(F)(F)c1ccccc1OOP(OOc1ccccc1C(F)(F)F)OOc1ccccc1C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
PPARG P37231 2/20 0.38
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
RXRG P48443 1/20 0.38
IDO1 P14902 2/20 0.37
MRGPRX1 Q96LB2 1/20 0.37
MRGPRX4 Q96LA9 1/20 0.36
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
LTA4H P09960 1/20 0.35
PTGS2 P35354 1/20 0.35
HSD11B1 P28845 1/20 0.34
NOTUM Q6P988 1/20 0.33
HTR1A P08908 1/20 0.33
SLC6A2 P23975 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15631713 0.77 PPARG (0.42) ADRA2AADRA2BADRA2CPPARGRXRA
SCHEMBL27510756 0.76 PPARG (0.41) ADRA2AADRA2BADRA2CPPARGRXRA
SCHEMBL11387279 0.75 PPARG (0.41) ADRA2AADRA2BADRA2CPPARGRXRA
SCHEMBL1685381 0.75 LTA4H (0.46) ADRA2AADRA2BADRA2CPPARGRXRA
Hydrochloric Acid SCHEMBL27597414 0.74 IDO1 (0.42) ADRA2AADRA2BADRA2CPPARGRXRA
SCHEMBL9242571 0.73 HSD11B1 (0.53) ADRA2AADRA2BADRA2CPPARGRXRA
SCHEMBL11048002 0.73 LTA4H (0.45) ADRA2AADRA2BADRA2CPPARGRXRA
Hydrochloric Acid SCHEMBL27460502 0.72 ADRA2A (0.40) ADRA2AADRA2BADRA2CPPARGRXRA
SCHEMBL6475202 0.72 PPARG (0.40) ADRA2AADRA2BADRA2CPPARGRXRA
SCHEMBL1053934 0.71 PPARG (0.41) ADRA2AADRA2BADRA2CPPARGRXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7682712-B2 Stability polymeric lubricants and thin film recording media comprising same SEAGATE TECHNOLOGY LLC (US) 2010-03-23 US claimed
US-20060089275-A1 Stability polymeric lubricants and thin film recording media comprising same SEAGATE TECHNOLOGY LC (US) 2006-04-27 US claimed
US-6995121-B1 Stability polymeric lubricants and thin film recording media comprising same SEAGATE TECHNOLOGY LLC (US) 2006-02-07 US claimed
US-6846542-B1 UV treatment for improving performance of lubricated thin film recording media and media obtained thereby SEAGATE TECHNOLOGY LLC (US) 2005-01-25 US claimed
US-7682712-B2 Stability polymeric lubricants and thin film recording media comprising same SEAGATE TECHNOLOGY LLC (US) 2010-03-23 US disclosed
US-20060089275-A1 Stability polymeric lubricants and thin film recording media comprising same SEAGATE TECHNOLOGY LC (US) 2006-04-27 US disclosed
US-6995121-B1 Stability polymeric lubricants and thin film recording media comprising same SEAGATE TECHNOLOGY LLC (US) 2006-02-07 US disclosed
US-6846542-B1 UV treatment for improving performance of lubricated thin film recording media and media obtained thereby SEAGATE TECHNOLOGY LLC (US) 2005-01-25 US disclosed