Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17002547 | 0.84 | ALOX15 (0.38) | ALOX15 | |
| SCHEMBL6489999 | 0.81 | — | — | |
| SCHEMBL14569839 | 0.81 | ALDH1A1 (0.42) | ALOX15 | |
| SCHEMBL458869 | 0.81 | SIGMAR1 (0.40) | ALOX15 | |
| SCHEMBL19853515 | 0.77 | ACHE (0.42) | ALOX15 | |
| SCHEMBL17002581 | 0.73 | ALDH1A1 (0.31) | ALOX15 | |
| SCHEMBL3555078 | 0.70 | ALDH1A1 (0.33) | — | |
| SCHEMBL9054481 | 0.70 | NPSR1 (0.53) | — | |
| SCHEMBL20474002 | 0.66 | DRD4 (0.43) | — | |
| SCHEMBL11512934 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6962911-B2 | Pyrrolopyrimidinone derivatives, process of preparation and use | SK CHEMICALS CO., LTD. (KR) | 2005-11-08 | — | — | US | disclosed |
| EP-1257553-B1 | PYRROLOPYRIMIDINONE DERIVATIVES, PROCESS OF PREPARATION AND USE | SK CHEMICALS CO LTD (KR) | 2004-05-26 | — | — | EP | disclosed |
| EP-1257553-A1 | PYRROLOPYRIMIDINONE DERIVATIVES, PROCESS OF PREPARATION AND USE | SK Chemicals Co., Ltd. (KR) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001060825-A1 | PYRROLOPYRIMIDINONE DERIVATIVES, PROCESS OF PREPARATION AND USE | SK CHEMICALS CO., LTD. (KR) | 2001-08-23 | — | — | WO | disclosed |