Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | ATM | Q13315 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053324 | 0.84 | P2RX7 (0.55) | LMNAMEN1KMT2AOPRM1P2RX7 | |
| SCHEMBL9052509 | 0.83 | P2RX7 (0.57) | P2RX7 | |
| SCHEMBL9052502 | 0.80 | DRD2 (0.54) | P2RX7 | |
| SCHEMBL9054788 | 0.78 | DRD3 (0.55) | USP2P2RX7 | |
| Hydrochloric Acid SCHEMBL9055462 | 0.77 | DRD3 (0.54) | LMNAMEN1KMT2AUSP2P2RX7 | |
| SCHEMBL14558083 | 0.75 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL7311276 | 0.75 | ATM (0.84) | LMNAATMMEN1KMT2AUSP2 | |
| Hydrochloric Acid SCHEMBL16226937 | 0.73 | ATM (0.82) | LMNAATMMEN1KMT2AUSP2 | |
| SCHEMBL19307814 | 0.72 | DRD4 (0.47) | ALDH1A1HTTMAPT | |
| SCHEMBL28518961 | 0.72 | KMT2A (0.66) | NPSR1LMNAATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706522-A1 | TETRAZOLE DERIVATIVES HAVING ANTIHISTAMINIC AND ANTIALLERGIC ACTIVITY | SUMITOMO METAL INDUSTRIES, LTD. (JP) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001350-A1 | TETRAZOLE DERIVATIVES HAVING ANTIHISTAMINIC AND ANTIALLERGIC ACTIVITY | SUMITOMO METAL INDUSTRIES, LTD. (JP) | 1995-01-12 | — | — | WO | disclosed |