SCHEMBL6475720

SCHEMBL6475720

C[C@@H]1OCC(=O)[C@H]1NC(=O)[C@H](CC(C)(C)CCc1ccccc1)NC(=O)c1ccoc1

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CTSK P43235 15/20 0.44
CTSL P07711 13/20 0.44
CTSS P25774 13/20 0.44
ITGAV P06756 1/20 0.34
ITGA2 P17301 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6476186 0.92 CTSK (0.45) CTSKCTSLCTSSITGAVITGA2
SCHEMBL6475741 0.91 CTSK (0.47) CTSKCTSLCTSS
SCHEMBL6486221 0.91 CTSL (0.55) CTSKCTSLCTSS
SCHEMBL6482887 0.87 CTSL (0.46) CTSKCTSLCTSS
SCHEMBL6476830 0.87 CTSK (0.50) CTSKCTSLCTSS
SCHEMBL6475961 0.86 CTSK (0.46) CTSKCTSLCTSSITGAVITGA2
SCHEMBL6591090 0.86 CTSK (0.36) CTSKCTSLCTSS
SCHEMBL6484502 0.86 CTSL (0.45) CTSKCTSLCTSS
SCHEMBL6484936 0.86 CTSK (0.61) CTSKCTSLCTSS
SCHEMBL6475422 0.86 CTSK (0.43) CTSKCTSLCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050020588-A1 Cysteine protease inhibitors PEPTIMMUNE, INC. 2005-01-27 US claimed
US-20050020588-A1 Cysteine protease inhibitors PEPTIMMUNE, INC. 2005-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050020588-A1 Cysteine protease inhibitors CTSS, CTSE, CTSV CTSK 4/4885CTSL 11/4885CTSS 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.