Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 2/20 | 0.34 |
| ▸ | GCGR | P47871 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.33 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4841580 | 0.92 | METAP2 (0.39) | METAP2LIPEGCGRHTR2CAMPD2 | |
| SCHEMBL14254846 | 0.90 | GCGR (0.35) | KCNN3METAP2LIPEGCGRHTR2C | |
| SCHEMBL6485047 | 0.89 | MCHR1 (0.35) | KCNN3METAP2LIPEGCGRMCHR1 | |
| SCHEMBL6477360 | 0.89 | GCGR (0.35) | KCNN3METAP2LIPEGCGREPHX2 | |
| SCHEMBL4847817 | 0.88 | KCNN3 (0.38) | KCNN3METAP2LIPEGCGRHTR2C | |
| SCHEMBL14254710 | 0.88 | KCNN3 (0.36) | KCNN3METAP2LIPEGCGRHTR2C | |
| SCHEMBL4845117 | 0.88 | KCNN3 (0.36) | KCNN3METAP2LIPEGCGRHTR2C | |
| SCHEMBL4848707 | 0.88 | KCNN3 (0.36) | KCNN3METAP2LIPEGCGRHTR2C | |
| SCHEMBL14254709 | 0.86 | GRM2 (0.37) | KCNN3LIPEHTR2CHCRTR1HCRTR2 | |
| SCHEMBL4848518 | 0.85 | CCR5 (0.34) | KCNN3METAP2LIPEGCGRCXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7342012-B2 | Inhibitors of αLβ2 mediated cell adhesion | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-03-11 | — | — | US | disclosed |
| US-7342012-B2 | Inhibitors of αLβ2 mediated cell adhesion | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-03-11 | — | — | US | disclosed |
| US-6897225-B1 | Inhibitors of αLβ2 mediated cell adhesion | TANABE SEIYAKU CO., LTD. (JP) | 2005-05-24 | — | — | US | disclosed |