Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16328702 | 0.89 | ALOX12 (0.54) | ALOX12MAPTKMT2AKDM4EPOLB | |
| SCHEMBL31115536 | 0.89 | ALOX12 (0.54) | ALOX12MAPTKMT2AKDM4EPOLB | |
| SCHEMBL6860661 | 0.89 | ALOX12 (0.54) | ALOX12MAPTKMT2AKDM4EPOLB | |
| SCHEMBL19646456 | 0.89 | ALOX12 (0.54) | ALOX12MAPTKMT2AKDM4EPOLB | |
| Triethylene Glycol SCHEMBL6478490 | 0.87 | KMT2A (0.56) | ALOX12MAPTKMT2AMEN1THRB | |
| SCHEMBL9506369 | 0.87 | ALOX12 (0.56) | ALOX12MAPTKMT2ATHRBKDM4E | |
| SCHEMBL12501215 | 0.81 | ALOX12 (0.53) | ALOX12MAPTKMT2AKDM4EPOLB | |
| SCHEMBL22891256 | 0.80 | FAAH (0.53) | ALOX12FAAHMGLL | |
| SCHEMBL863059 | 0.79 | KMT2A (0.41) | MAPTKMT2AMEN1THRBHTT | |
| SCHEMBL5821258 | 0.79 | KMT2A (0.41) | MAPTKMT2AMEN1THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6956051-B1 | Enkephalin conjugates | NOBEX CORPORATION (US) | 2005-10-18 | — | — | US | disclosed |
| US-6943148-B1 | Methods for delivering therapeutics across blood-barrier and for altering receptor binding affinity | NOBEX CORPORATION (US) | 2005-09-13 | — | — | US | disclosed |
| US-6930090-B2 | Methods of activating a receptor using amphiphilic drug-oligomer conjugates | NOBEX CORPORATION (US) | 2005-08-16 | — | — | US | disclosed |
| US-20040110735-A1 | Methods of activating receptor using amphiphilic drug-oligomer conjugates | BIOCON LIMITED (IN) | 2004-06-10 | — | — | US | disclosed |
| US-6703381-B1 | ADMINISTERING AMPHIPHILIC ENKEPHALIN-OLIGOMER CONJUGATE | NOBEX CORPORATION | 2004-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110735-A1 | Methods of activating receptor using amphiphilic drug-oligomer conjugates | OGFR, NGFR, LDLR | ALOX12 1520/4885MAPT 1794/4885KMT2A 4399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.