Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19646456 | 1.00 | ALOX12 (0.54) | ALOX12LMNASMN1; SMN2HPGDFAAH | |
| SCHEMBL6860661 | 1.00 | ALOX12 (0.54) | ALOX12LMNASMN1; SMN2HPGDFAAH | |
| SCHEMBL31115536 | 1.00 | ALOX12 (0.54) | ALOX12LMNASMN1; SMN2HPGDFAAH | |
| SCHEMBL9506369 | 0.98 | ALOX12 (0.56) | ALOX12LMNASMN1; SMN2HPGDFAAH | |
| SCHEMBL12501215 | 0.92 | ALOX12 (0.53) | ALOX12LMNASMN1; SMN2HPGDFAAH | |
| SCHEMBL22891256 | 0.90 | FAAH (0.53) | ALOX12FAAHMGLLLPAR1LPAR3 | |
| SCHEMBL6478495 | 0.89 | ALOX12 (0.45) | ALOX12LMNASMN1; SMN2HPGDFAAH | |
| Triethylene Glycol SCHEMBL6478490 | 0.87 | KMT2A (0.56) | ALOX12LMNASMN1; SMN2HPGDKMT2A | |
| SCHEMBL4587864 | 0.83 | ALOX12 (0.47) | ALOX12LMNASMN1; SMN2HPGDFAAH | |
| SCHEMBL27847323 | 0.80 | ALOX12 (0.47) | ALOX12LMNASMN1; SMN2HPGDFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11793885-B2 | Substituted benzo[5,6][1,4]diazepino[1,2-a]indoles for the treatment of proliferative disorders | IMMUNOGEN, INC. (US) | 2023-10-24 | — | — | US | disclosed |
| US-20200397914-A1 | BENZODIAZEPINE DERIVATIVES | IMMUNOGEN, INC. | 2020-12-24 | — | — | US | disclosed |
| US-20200338233-A1 | METHODS, POLYMER-CONTAINING FORMULATIONS, AND POLYMER COMPOSITIONS FOR TREATING RETINAL DETACHMENT AND OTHER OCULAR DISORDERS | Pykus Therapeutics, Inc. (US) | 2020-10-29 | — | — | US | disclosed |
| US-10683389-B2 | Beads for nucleic acid sequencing | GENAPSYS, INC. (US) | 2020-06-16 | — | — | US | disclosed |
| US-20180105638-A1 | BEADS FOR NUCLEIC ACID SEQUENCING | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2018-04-19 | — | — | US | disclosed |
| US-20100252433-A1 | NOVEL OPTICAL LABELING MOLECULES FOR PROTEOMICS AND OTHER BIOLOGICAL ANALYSES | NATIONAL SCIENCE FOUNDATION | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100252433-A1 | NOVEL OPTICAL LABELING MOLECULES FOR PROTEOMICS AND OTHER BIOLOGICAL ANALYSES | PTMS, CHAMP1, RAB5IF | ALOX12 1800/4885LMNA 3234/4885SMN1; SMN2 4339/4885 |
| US-20200397914-A1 | BENZODIAZEPINE DERIVATIVES | GABRA5, GABRA3, GABRA1 | ALOX12 3369/4885LMNA 2755/4885SMN1; SMN2 2352/4885 |
| US-11793885-B2 | Substituted benzo[5,6][1,4]diazepino[1,2-a]indoles for the treatment of proliferative disorders | MKI67, GABBR1, GABBR2 | ALOX12 2679/4885LMNA 2428/4885SMN1; SMN2 3393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.