Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.53 |
| ▸ | MGLL | Q99685 | 3/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.41 |
| ▸ | TK1 | P04183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16328702 | 0.90 | ALOX12 (0.54) | FAAHMGLLALOX12LPAR1LPAR2 | |
| SCHEMBL6860661 | 0.90 | ALOX12 (0.54) | FAAHMGLLALOX12LPAR1LPAR2 | |
| SCHEMBL19646456 | 0.90 | ALOX12 (0.54) | FAAHMGLLALOX12LPAR1LPAR2 | |
| SCHEMBL31115536 | 0.90 | ALOX12 (0.54) | FAAHMGLLALOX12LPAR1LPAR2 | |
| SCHEMBL9506369 | 0.88 | ALOX12 (0.56) | FAAHMGLLALOX12 | |
| SCHEMBL12501215 | 0.82 | ALOX12 (0.53) | FAAHMGLLALOX12 | |
| SCHEMBL6478495 | 0.80 | ALOX12 (0.45) | FAAHMGLLALOX12 | |
| SCHEMBL9927889 | 0.80 | FAAH (0.46) | FAAHMGLL | |
| SCHEMBL9927884 | 0.77 | MGLL (0.52) | FAAHMGLL | |
| SCHEMBL23771806 | 0.76 | FAAH (0.48) | FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3432874-B1 | METHODS AND COMPOSITIONS FOR TREATMENT OF PRADER-WILLI SYNDROME | YISSUM RES DEV CO OF HEBREW UNIV JERUSALEM LTD (IL) | 2021-01-13 | — | — | EP | disclosed |