Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.49 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6478722 | 0.99 | LMNA (0.51) | LMNAOPRM1OPRD1OPRK1P2RX3 | |
| Hydrochloric Acid SCHEMBL6478708 | 0.99 | LMNA (0.51) | LMNAOPRM1OPRD1OPRK1P2RX3 | |
| Hydrochloric Acid SCHEMBL6478980 | 0.85 | OPRM1 (0.60) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL6478982 | 0.85 | OPRM1 (0.60) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL21656974 | 0.83 | LMNA (0.60) | LMNAOPRM1OPRD1OPRK1P2RX3 | |
| SCHEMBL23210676 | 0.81 | LMNA (0.61) | LMNAOPRM1OPRD1OPRK1P2RX3 | |
| SCHEMBL21144955 | 0.80 | LOXL2 (0.61) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL18920591 | 0.80 | LOXL2 (0.61) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL21656679 | 0.80 | LMNA (0.56) | LMNAOPRM1OPRD1OPRK1P2RX3 | |
| SCHEMBL6478754 | 0.80 | LMNA (0.47) | LMNAOPRM1OPRD1OPRK1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043358-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-02-24 | — | — | US | disclosed |
| US-20020143034-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2002-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143034-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB1, ADRB2, ADRB3 | LMNA 626/4885OPRM1 19/4885OPRD1 17/4885 |
| US-20050043358-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB2, ADRB1, ADRB3 | LMNA 611/4885OPRM1 33/4885OPRD1 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.