Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5649476 | 0.78 | RAB9A (0.39) | ALDH1A1MAPTTDP1KDM4EMEN1 | |
| SCHEMBL9928122 | 0.76 | MAPT (0.32) | ALDH1A1MAPTTDP1LMNAHTT | |
| SCHEMBL10081334 | 0.76 | KMT2A (0.33) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6479818 | 0.76 | MAPT (0.38) | ALDH1A1MAPTTDP1LMNAHTT | |
| SCHEMBL10102269 | 0.74 | MAPT (0.36) | ALDH1A1MAPTTDP1LMNAKDM4E | |
| SCHEMBL9928123 | 0.74 | BRAF (0.35) | ALDH1A1MAPTTDP1LMNAHTT | |
| SCHEMBL7115389 | 0.74 | KMT2A (0.36) | MAPTTDP1LMNAHTTMEN1 | |
| SCHEMBL6492241 | 0.73 | ALDH1A1 (0.37) | ALDH1A1MAPTTDP1LMNAHTT | |
| SCHEMBL12659492 | 0.71 | MAPT (0.35) | ALDH1A1MAPTTDP1LMNAHTT | |
| SCHEMBL6480463 | 0.71 | MAPT (0.35) | ALDH1A1MAPTTDP1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6863843-B2 | Naphthopyran compounds, photoresponsive compositions and lenses | VISION-EASE LENS, INC. (US) | 2005-03-08 | — | — | US | disclosed |
| US-20020080451-A1 | Novel naphthopyran compounds, photoresponsive compositions and lenses | VISION-EASE LENS, INC. | 2002-06-27 | — | — | US | disclosed |