Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 4/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960075 | 0.86 | GPR88 (0.59) | ANPEPMMP1FOLH1MMEMMP3 | |
| SCHEMBL8653691 | 0.85 | MAPK1 (0.53) | ANPEPFOLH1MMEALDH1A1 | |
| SCHEMBL6481469 | 0.82 | SMN1; SMN2 (0.52) | TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL6474769 | 0.80 | MMP9 (0.48) | MMP1MMEMMP3MMP9MMP2 | |
| SCHEMBL6474666 | 0.79 | MME (0.52) | ANPEPFOLH1MME | |
| SCHEMBL6474415 | 0.78 | CYP2C9 (0.47) | ALDH1A1 | |
| SCHEMBL28022564 | 0.78 | CTSS (0.64) | CTSLCTSSCTSKTAS1R3TAS1R1 | |
| Acetylleucine SCHEMBL27406784 | 0.77 | ALDH1A1 (0.59) | ANPEPMMP1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL5869765 | 0.77 | FOLH1 (0.52) | ANPEPFOLH1CTSLCTSSCTSB | |
| SCHEMBL15251955 | 0.77 | HTT (0.58) | ANPEPMMP1FOLH1MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6939888-B2 | 1-H-3-arylpirrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2005-09-06 | — | — | US | disclosed |
| US-20040019061-A1 | 1-H-3-arylpirrolidine-2,4-dione derivatives | FISCHER REINER (DE) | 2004-01-29 | — | — | US | disclosed |
| US-6472419-B1 | 1-H-3-aryl-pyrrolidine-2, 4-dione derivatives as pest-control agents | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019061-A1 | 1-H-3-arylpirrolidine-2,4-dione derivatives | PRXL2A, DDT, CYP4B1 | ANPEP 2333/4885MMP1 3464/4885FOLH1 4022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.