Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | AURKA | O14965 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6482639 | 0.89 | AURKA (0.41) | MAPTAURKAMEN1KMT2AUSP2 | |
| SCHEMBL6480285 | 0.87 | AURKA (0.53) | MAPTAURKAMEN1KMT2AUSP2 | |
| SCHEMBL6481407 | 0.87 | AURKA (0.47) | MAPTAURKAMEN1KMT2AUSP2 | |
| SCHEMBL6472908 | 0.84 | TTBK1 (0.43) | MAPTAURKAMEN1KMT2AUSP2 | |
| SCHEMBL5204622 | 0.84 | SCN9A (0.51) | AURKA | |
| SCHEMBL6474471 | 0.84 | BCL6 (0.49) | MAPTAURKAMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL5203439 | 0.83 | SCN9A (0.50) | AURKA | |
| SCHEMBL1375252 | 0.79 | MAPT (0.41) | MAPTMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL5206436 | 0.74 | MAPT (0.38) | MAPTMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL7157258 | 0.74 | MERTK (0.42) | MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916820-B1 | Neurotrophic substituted pyrimidines | KRENITSKY PHARMACEUTICALS, INC. (US) | 2005-07-12 | — | — | US | claimed |