Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.43 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | MGMT | P16455 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | BCL6 | P41182 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6480285 | 0.88 | AURKA (0.53) | TTBK1TTBK2MEN1KMT2ANPC1 | |
| SCHEMBL6481407 | 0.88 | AURKA (0.47) | TTBK1TTBK2MEN1KMT2ANPC1 | |
| SCHEMBL5204622 | 0.88 | SCN9A (0.51) | TTBK1TTBK2AURKABCL6KCNH2 | |
| SCHEMBL6474471 | 0.87 | BCL6 (0.49) | TTBK1TTBK2MEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL5203439 | 0.86 | SCN9A (0.50) | TTBK1TTBK2AURKABCL6KCNH2 | |
| SCHEMBL6480339 | 0.84 | MAPT (0.44) | MEN1KMT2ANPC1RAB9AAURKA | |
| SCHEMBL6482639 | 0.81 | AURKA (0.41) | MEN1KMT2ANPC1RAB9AAURKA | |
| SCHEMBL6474012 | 0.77 | BCL6 (0.52) | TTBK1TTBK2MEN1KMT2AAURKA | |
| SCHEMBL5206828 | 0.76 | MAPT (0.39) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL6482628 | 0.75 | BCL6 (0.44) | AURKAMAPTBCL6KDM4EKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916820-B1 | Neurotrophic substituted pyrimidines | KRENITSKY PHARMACEUTICALS, INC. (US) | 2005-07-12 | — | — | US | claimed |