Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5204622 | 0.87 | SCN9A (0.51) | BCL6SCN5ASCN9ATTBK1TTBK2 | |
| SCHEMBL6472908 | 0.87 | TTBK1 (0.43) | BCL6MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6480285 | 0.87 | AURKA (0.53) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6481407 | 0.87 | AURKA (0.47) | BCL6MAPTMEN1GAAKMT2A | |
| SCHEMBL6480339 | 0.84 | MAPT (0.44) | MAPTMEN1GAAKMT2AALDH1A1 | |
| SCHEMBL6474012 | 0.84 | BCL6 (0.52) | BCL6MAPTMEN1GAAKMT2A | |
| SCHEMBL6473796 | 0.81 | MAPT (0.51) | MAPTMEN1GAAKMT2AALDH1A1 | |
| SCHEMBL6482639 | 0.81 | AURKA (0.41) | MAPTMEN1GAAKMT2AALDH1A1 | |
| SCHEMBL6482628 | 0.77 | BCL6 (0.44) | BCL6MAPTGAAALDH1A1LMNA | |
| SCHEMBL5204374 | 0.73 | SCN9A (0.44) | BCL6MAPTMEN1KMT2ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916820-B1 | Neurotrophic substituted pyrimidines | KRENITSKY PHARMACEUTICALS, INC. (US) | 2005-07-12 | — | — | US | claimed |