Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 9/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491491 | 0.80 | F2R (0.51) | MAPTPOLBSMN1; SMN2GAAKMT2A | |
| SCHEMBL6480497 | 0.80 | UBE2M (0.46) | MAPTPOLBSMN1; SMN2KMT2ATYK2 | |
| SCHEMBL6490737 | 0.78 | NPSR1 (0.46) | RAB9ASMN1; SMN2GAAKMT2AALDH1A1 | |
| SCHEMBL6481370 | 0.78 | NPSR1 (0.49) | SMN1; SMN2GAAALDH1A1TYK2USP2 | |
| SCHEMBL6490018 | 0.78 | ALDH1A1 (0.47) | MAPTPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6481498 | 0.74 | TSHR (0.44) | MAPTNPC1KMT2AALDH1A1IDH1 | |
| SCHEMBL6186086 | 0.71 | MAPT (0.39) | MAPTSMN1; SMN2THRBKMT2AALDH1A1 | |
| SCHEMBL6229816 | 0.70 | RORC (0.43) | MAPTPOLBSMN1; SMN2GAAKMT2A | |
| SCHEMBL6492205 | 0.67 | MAPT (0.41) | MAPTPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6206223 | 0.67 | F2R (0.53) | MAPTNPC1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050215614-A1 | Substituted indoles and their use as hcv inhibitors | RIGEL PHARMACEUTICALS, INC. (US) | 2005-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215614-A1 | Substituted indoles and their use as hcv inhibitors | IDO1, IDO2, HAVCR2 | CHRNA7 3442/4885MAPT 3587/4885POLB 4303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.