SCHEMBL6480696

SCHEMBL6480696

Cc1nnn(CCOc2c(Cl)ccc(C(=O)OC3=CC(=O)CCC3)c2Cl)n1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 1/20 0.31
HPD P32754 2/20 0.31
ENPP2 Q13822 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6481018 0.84 HPD (0.31) HPGDHPD
SCHEMBL6482084 0.83 ENPP2 (0.34) ENPP2
SCHEMBL6482410 0.81 BAZ2B (0.39) LMNAHPGDHTTSMN1; SMN2ALDH1A1
SCHEMBL6480901 0.80 MAPK1 (0.35) LMNA
SCHEMBL6492362 0.80 SMN1; SMN2 (0.38) LMNAHPGDHTTSMN1; SMN2ALDH1A1
SCHEMBL6480978 0.80 LMNA (0.38) LMNAHPGDHTTSMN1; SMN2ALDH1A1
SCHEMBL6494736 0.79 ENPP2 (0.32) ENPP2
SCHEMBL6479128 0.79 HTR4 (0.32)
SCHEMBL6493649 0.79
SCHEMBL6481368 0.78 HPGD (0.38) LMNAHPGDHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050090398-A1 Novel tetrazole derivative useful as herbicides YANAGI AKIHIKO (JP) 2005-04-28 US disclosed
EP-1476437-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES Bayer CropScience AG (DE) 2004-11-17 EP disclosed
WO-2003066607-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-08-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090398-A1 Novel tetrazole derivative useful as herbicides DDT, TTI1, CYP1A1 LMNA 4295/4885HPGD 4216/4885HTT 616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.