SCHEMBL6480908

SCHEMBL6480908

CC(=O)c1ccccc1CCCC(Cl)(Cl)Cl

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.41
ALDH1A1 P00352 4/20 0.41
FOLH1 Q04609 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
KDM4E B2RXH2 2/20 0.38
ADRB2 P07550 1/20 0.36
SLC16A3 O15427 5/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP2D6 P10635 1/20 0.36
MAPT P10636 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HTT P42858 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9131501 0.79 LMNA (0.42) LMNAALDH1A1FOLH1SMN1; SMN2KDM4E
SCHEMBL10420414 0.79 LMNA (0.45) LMNAALDH1A1FOLH1SMN1; SMN2KDM4E
SCHEMBL1131361 0.79 TSHR (0.46) LMNAALDH1A1FOLH1CYP3A4CYP2D6
SCHEMBL7498472 0.77 LMNA (0.44) LMNAALDH1A1FOLH1SMN1; SMN2KDM4E
SCHEMBL298005 0.77 LIPG (0.53) LMNAALDH1A1CYP3A4HTT
SCHEMBL7991923 0.77 ALDH1A1 (0.44) LMNAALDH1A1FOLH1SMN1; SMN2KDM4E
SCHEMBL30664751 0.77 LMNA (0.44) LMNAALDH1A1FOLH1SMN1; SMN2KDM4E
SCHEMBL10422004 0.77 LMNA (0.44) LMNAALDH1A1FOLH1SMN1; SMN2KDM4E
SCHEMBL14397902 0.77 ALDH1A1 (0.46) LMNAALDH1A1FOLH1SMN1; SMN2KDM4E
SCHEMBL5709997 0.76 LIPG (0.56) LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12448487-B2 Polysiloxanes with radiation- and moisture-cross-linkable groups WACKER CHEMIE AG (DE) 2025-10-21 US disclosed
CN-115397891-B Polysiloxanes with radiation-crosslinkable and moisture-crosslinkable groups 瓦克化学股份公司 2024-02-02 CN disclosed
US-20230167246-A1 Polysiloxanes with radiation- and moisture-cross-linkable groups WACKER CHEMIE AG (DE) 2023-06-01 US disclosed
EP-4136137-A1 POLYSILOXANES WITH RADIATION- AND MOISTURE-CROSS-LINKABLE GROUPS Wacker Chemie AG (DE) 2023-02-22 EP disclosed
WO-2021209113-A1 POLYSILOXANES WITH RADIATION- AND MOISTURE-CROSS-LINKABLE GROUPS WACKER CHEMIE AG (DE) 2021-10-21 WO disclosed
US-6846852-B2 Siloxane-containing compositions curable by radiation to silicone elastomers GOLDSCHMIDT AG (DE) 2005-01-25 US disclosed
US-20030064232-A1 Siloxane-containing compositions curable by radiation to silicone elastomers EVONIK GOLDSCHMIDT GMBH (DE) 2003-04-03 US disclosed
WO-2003016403-A1 SILOXANE-CONTAINING COMPOSITIONS CURABLE BY RADIATION TO SILICONE ELASTOMERS GOLDSCHMIDT AG (DE) 2003-02-27 WO disclosed
EP-0590020-B1 CURABLE ORGANOPOLYSILOXANE PREPARATIONS WACKER CHEMIE GMBH (DE) 1995-09-06 EP disclosed
US-5420222-A Curable organo(poly)siloxane compositions WACKER-CHEMIE GMBH (DE) 1995-05-30 US disclosed
EP-0169295-B1 POLYSILOXANES, PROCESS FOR PREPARING THEM AND THEIR USE Wacker-Chemie GmbH (DE) 1988-06-15 EP disclosed
EP-0237757-A2 Compositions convertible into elastomers by irradiation Wacker-Chemie GmbH (DE) 1987-09-23 EP disclosed
US-4605567-A PHOTOPOLYMERIZATION OF ALLYL ANHYDRIDE-MODIFIED POLYSILOXANES REACTED WITH HYDROXYETHYL ACRYLATE WACKER-CHEMIE GMBH (DE) 1986-08-12 US disclosed
EP-0186099-A2 Crosslinkable organopolysiloxanes, process for their preparation and use of these organopolysiloxanes Wacker-Chemie GmbH (DE) 1986-07-02 EP disclosed
US-4597987-A Organopolysiloxanes containing both acryloxyalkyl groups and Si-bonded hydrogen atoms in the same molecule WACKER-CHEMIE GMBH (DE) 1986-07-01 US disclosed
US-4571349-A Crosslinkable organopolysiloxanes and a method for preparing the same WACKER-CHEMIE GMBH (DE) 1986-02-18 US disclosed
EP-0169295-A2 Polysiloxanes, process for preparing them and their use Wacker-Chemie GmbH (DE) 1986-01-29 EP disclosed
US-4554339-A PROTECTIVE COATINGS, SILICON-BONDED HYDROGEN WACKER-CHEMIE GMBH (DE) 1985-11-19 US disclosed
EP-0156036-A2 Organopolysiloxanes and by light irradiation crosslinkable materials containing these polysiloxanes Wacker-Chemie GmbH (DE) 1985-10-02 EP disclosed
EP-0097333-A2 Organopolysiloxanes, process for their production and their use Wacker-Chemie GmbH (DE) 1984-01-04 EP disclosed