Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | GAA | P10253 | 7/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6739761 | 0.87 | MEN1 (0.41) | ALDH1A1GAATDP1KDM4EL3MBTL1 | |
| SCHEMBL5685489 | 0.87 | ALDH1A1 (0.71) | ALDH1A1GAATDP1KDM4EL3MBTL1 | |
| SCHEMBL6483746 | 0.80 | MEN1 (0.47) | ALDH1A1GAATDP1KDM4EL3MBTL1 | |
| SCHEMBL6740875 | 0.80 | MEN1 (0.36) | ALDH1A1GAATDP1KDM4EL3MBTL1 | |
| SCHEMBL6490146 | 0.80 | CASR (0.53) | ALDH1A1TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL6739233 | 0.78 | ALDH1A1 (0.46) | ALDH1A1GAATDP1KDM4EL3MBTL1 | |
| SCHEMBL6535654 | 0.78 | TDP1 (0.48) | ALDH1A1GAATDP1KDM4EMEN1 | |
| SCHEMBL6734145 | 0.76 | MEN1 (0.43) | ALDH1A1GAATDP1KDM4EMEN1 | |
| SCHEMBL6740811 | 0.75 | MEN1 (0.36) | ALDH1A1GAATDP1KDM4EL3MBTL1 | |
| SCHEMBL15003942 | 0.72 | ALDH1A1 (0.82) | ALDH1A1GAATDP1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951574-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY (US) | 2005-10-04 | — | — | US | disclosed |
| US-20040255403-A1 | Primary intermediates for oxidative coloration of hair | LIM MU-ILL (US) | 2004-12-23 | — | — | US | disclosed |
| US-6780999-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY | 2004-08-24 | — | — | US | disclosed |
| EP-1353895-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-Clairol, Inc. (US) | 2003-10-22 | — | — | EP | disclosed |
| US-20020144357-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-10-10 | — | — | US | disclosed |
| WO-2002058632-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-CLARIOL, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040255403-A1 | Primary intermediates for oxidative coloration of hair | COX5A, CYC1, MT-CO1 | ALDH1A1 7/4885GAA 4142/4885TDP1 2250/4885 |
| US-20020144357-A1 | Primary intermediates for oxidative coloration of hair | COX5A, CYC1, MT-CO1 | ALDH1A1 7/4885GAA 4142/4885TDP1 2250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.