Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.71 |
| ▸ | MEN1 | O00255 | 6/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | GAA | P10253 | 5/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6484587 | 0.87 | ALDH1A1 (0.52) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL5682687 | 0.82 | KMT2A (0.68) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL5685477 | 0.80 | CASR (0.51) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL3975247 | 0.78 | TDP1 (0.46) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL6739761 | 0.73 | MEN1 (0.41) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL5682803 | 0.73 | PDE10A (0.45) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL5681756 | 0.72 | MEN1 (0.48) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL8140503 | 0.70 | PDE10A (0.45) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL31490417 | 0.70 | ALDH1A1 (0.56) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL7162593 | 0.70 | CA1 (0.64) | ALDH1A1MEN1KMT2AGAANR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1359891-B1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2006-03-15 | — | — | EP | disclosed |
| US-6838561-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY (US) | 2005-01-04 | — | — | US | disclosed |
| EP-1359891-A4 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2004-12-01 | — | — | EP | disclosed |
| EP-1359891-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-Clairol, Inc. (US) | 2003-11-12 | — | — | EP | disclosed |
| US-20020144358-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-10-10 | — | — | US | disclosed |
| WO-2002062308-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-CLAIROL, INC. (US) | 2002-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020144358-A1 | Primary intermediates for oxidative coloration of hair | COX5A, CYC1, MT-CO1 | ALDH1A1 7/4885TDP1 2192/4885MEN1 3545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.