Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5685477 | 0.86 | CASR (0.51) | CASRL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL6477442 | 0.82 | POLB (0.54) | CASRMEN1KMT2AADRB2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7770226 | 0.82 | POLB (0.43) | TDP1MAPK1SLC6A4KMT2AADRB2 | |
| Hydrochloric Acid SCHEMBL6269419 | 0.81 | POLB (0.53) | CASRMEN1KMT2AADRB2CYP3A4 | |
| SCHEMBL6484587 | 0.80 | ALDH1A1 (0.52) | L3MBTL1TDP1MAPK1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6273752 | 0.80 | ALDH1A1 (0.40) | L3MBTL1TDP1MAPK1ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL6274840 | 0.79 | MEN1 (0.41) | MAPK1MEN1KMT2AADRB2CYP3A4 | |
| Hydrochloric Acid SCHEMBL6274790 | 0.77 | MITF (0.43) | L3MBTL1TDP1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL6268528 | 0.76 | MAPT (0.44) | L3MBTL1TDP1MAPK1MEN1KMT2A | |
| SCHEMBL5267654 | 0.75 | CASR (0.53) | CASRL3MBTL1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951574-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY (US) | 2005-10-04 | — | — | US | disclosed |
| US-20040255403-A1 | Primary intermediates for oxidative coloration of hair | LIM MU-ILL (US) | 2004-12-23 | — | — | US | disclosed |
| US-6780999-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY | 2004-08-24 | — | — | US | disclosed |
| EP-1353895-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-Clairol, Inc. (US) | 2003-10-22 | — | — | EP | disclosed |
| US-20020144357-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-10-10 | — | — | US | disclosed |
| WO-2002058632-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-CLARIOL, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040255403-A1 | Primary intermediates for oxidative coloration of hair | COX5A, CYC1, MT-CO1 | CASR 4858/4885L3MBTL1 4152/4885TDP1 2250/4885 |
| US-20020144357-A1 | Primary intermediates for oxidative coloration of hair | COX5A, CYC1, MT-CO1 | CASR 4858/4885L3MBTL1 4152/4885TDP1 2250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.