Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 13/20 | 0.33 |
| ▸ | ACHE | P22303 | 13/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6483879 | 0.85 | ACHE (0.33) | BCHEACHEHRH3KDM4EPOLB | |
| SCHEMBL5406203 | 0.77 | HSD17B10 (0.32) | BCHEACHEHSD17B10POLBL3MBTL1 | |
| SCHEMBL5348192 | 0.75 | ADORA3 (0.33) | BCHEACHEKDM4EPOLBL3MBTL1 | |
| SCHEMBL5355565 | 0.74 | POLB (0.33) | BCHEACHEHSD17B10KDM4EPOLB | |
| SCHEMBL5368947 | 0.71 | BCHE (0.36) | BCHEACHELMNAHTT | |
| SCHEMBL6477156 | 0.71 | HTT (0.33) | BCHEPOLBLMNAHTT | |
| SCHEMBL5406199 | 0.70 | BCHE (0.32) | BCHEACHEHSD17B10HRH3POLB | |
| SCHEMBL5355562 | 0.69 | BCHE (0.32) | BCHEACHEPOLBLMNAHTT | |
| SCHEMBL5366471 | 0.64 | HTT (0.35) | BCHEACHEPOLBLMNAHTT | |
| SCHEMBL6700923 | 0.64 | MAPT (0.36) | BCHEACHEHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949649-B2 | Thioether substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES CO. (US) | 2005-09-27 | — | — | US | disclosed |
| US-20040097736-A1 | Thioether substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097736-A1 | Thioether substituted imidazoquinolines | IFNG, IRF3, IL2 | BCHE 4028/4885ACHE 4781/4885HSD17B10 3698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.