Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.39 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 3/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079066 | 1.00 | CTSK (0.39) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL7079069 | 1.00 | CTSK (0.39) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL6991042 | 1.00 | CTSK (0.39) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL7121346 | 0.87 | CTSK (0.48) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL7121352 | 0.87 | CTSK (0.48) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL31402214 | 0.87 | CTSK (0.48) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL30150868 | 0.80 | CA1 (0.42) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL30148499 | 0.80 | CA1 (0.42) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL15797149 | 0.80 | CA1 (0.42) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL2418915 | 0.77 | CTSK (0.49) | CTSKCTSSCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050020588-A1 | Cysteine protease inhibitors | PEPTIMMUNE, INC. | 2005-01-27 | — | — | US | disclosed |
| US-20040053921-A1 | Amidino and guanidino peptidyl compounds useful for treating autoimmune diseases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020588-A1 | Cysteine protease inhibitors | CTSS, CTSE, CTSV | CTSK 4/4885CTSS 1/4885CA1 539/4885 |
| US-20040053921-A1 | Amidino and guanidino peptidyl compounds useful for treating autoimmune diseases | CTSK, CTSS, CTSB | CTSK 1/4885CTSS 2/4885CA1 1698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.