Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KIF11 | P52732 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6872397 | 1.00 | LDHA (0.46) | LDHAMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL7015543 | 1.00 | LDHA (0.46) | LDHAMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL606118 | 0.82 | KIF11 (0.44) | KMT2AKIF11LMNACYP1A2MAPT | |
| SCHEMBL7540245 | 0.81 | LDHA (0.46) | LDHAMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL27839176 | 0.78 | LDHA (0.45) | LDHAKIF11ALDH1A1LMNAALOX15 | |
| SCHEMBL4653290 | 0.76 | LDHA (0.50) | LDHAKIF11ALDH1A1LMNAALOX15 | |
| SCHEMBL10980312 | 0.75 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1LMNAALOX15 | |
| SCHEMBL27866045 | 0.75 | PPARG (0.47) | LDHAMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL8457734 | 0.74 | KIF11 (0.54) | LDHAMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL29226417 | 0.73 | ALDH1A1 (0.46) | LDHAKMT2AKIF11ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881839-B2 | Process for preparing diltiazem using a heterogeneous trifunctional catalyst | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-04-19 | — | — | US | claimed |
| US-20040127704-A1 | Process for preparing diltiazem using a heterogeneous trifunctional catalyst | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-07-01 | — | — | US | claimed |
| US-6881839-B2 | Process for preparing diltiazem using a heterogeneous trifunctional catalyst | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-04-19 | — | — | US | disclosed |
| WO-2004058734-A1 | PROCESS FOR PREPARING DILTIAZEM USING A HETEROGENEOUS TRIFUNCTIONAL CATALYST | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-07-15 | — | — | WO | disclosed |
| US-20040127704-A1 | Process for preparing diltiazem using a heterogeneous trifunctional catalyst | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127704-A1 | Process for preparing diltiazem using a heterogeneous trifunctional catalyst | CYP2W1, INMT, TST | LDHA 1660/4885MEN1 4650/4885KMT2A 1171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.