⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6642225 | 0.82 | PADI4 (0.32) | — | |
| SCHEMBL6485082 | 0.80 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL6641959 | 0.65 | IKBKB (0.36) | — | |
| SCHEMBL30839543 | 0.61 | ALDH1A1 (0.44) | — | |
| SCHEMBL6642545 | 0.61 | LPO (0.34) | — | |
| SCHEMBL7367897 | 0.58 | MPO (0.35) | — | |
| SCHEMBL29920871 | 0.57 | MEN1 (0.33) | — | |
| SCHEMBL18268687 | 0.54 | LPO (0.34) | — | |
| SCHEMBL28343442 | 0.54 | KDM4E (0.38) | — | |
| SCHEMBL2202785 | 0.54 | APOBEC3A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1312153-C | Pyrrolopyrimidinone derivatives, process for their preparation and their use | SK CHEMICALS CO LTD (KR) | 2007-04-25 | — | — | CN | disclosed |
| US-6962911-B2 | Pyrrolopyrimidinone derivatives, process of preparation and use | SK CHEMICALS CO., LTD. (KR) | 2005-11-08 | — | — | US | disclosed |
| EP-1257553-B1 | PYRROLOPYRIMIDINONE DERIVATIVES, PROCESS OF PREPARATION AND USE | SK CHEMICALS CO LTD (KR) | 2004-05-26 | — | — | EP | disclosed |
| US-20030171361-A1 | Pyrrolopyrimidinone derivatives, process of preparation and use | SK CHEMICALS CO., LTD. (KR) | 2003-09-11 | — | — | US | disclosed |
| CN-1422271-A | Pyrrolopyrimidinone derivatives, process for their preparation and their use | SK CHEMICALS CO LTD (KR) | 2003-06-04 | — | — | CN | disclosed |