Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | DCTPP1 | Q9H773 | 8/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497679 | 0.83 | MCL1 (0.40) | DCTPP1 | |
| SCHEMBL6486754 | 0.83 | MCL1 (0.37) | LMNASMN1; SMN2DCTPP1PPARGALDH1A1 | |
| SCHEMBL6498502 | 0.82 | ALOX5AP (0.37) | LMNASMN1; SMN2DCTPP1PPARGPIK3C2B | |
| SCHEMBL6490392 | 0.80 | BCL2 (0.44) | PIK3C2B | |
| SCHEMBL6490845 | 0.79 | OPRL1 (0.38) | LMNASMN1; SMN2DCTPP1ALDH1A1MAPT | |
| SCHEMBL6501531 | 0.79 | ALDH1A1 (0.38) | LMNASMN1; SMN2PPARGALDH1A1MAPT | |
| SCHEMBL6491248 | 0.78 | DCTPP1 (0.38) | LMNASMN1; SMN2DCTPP1MAPTKDM4E | |
| SCHEMBL6490954 | 0.78 | TSHR (0.42) | LMNASMN1; SMN2DCTPP1PPARGCYP1A2 | |
| SCHEMBL6490596 | 0.74 | MCL1 (0.38) | LMNASMN1; SMN2DCTPP1PPARGALDH1A1 | |
| SCHEMBL6498538 | 0.74 | DCTPP1 (0.44) | LMNADCTPP1PPARGPIK3C2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | LMNA 3711/4885SMN1; SMN2 1128/4885DCTPP1 1534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.