SCHEMBL6498538

SCHEMBL6498538

Cc1cc(Br)cc2c1nc(C)n2Cc1ccccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DCTPP1 Q9H773 2/20 0.44
GALR3 O60755 2/20 0.44
NR2F2 P24468 2/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
BRD4 O60885 1/20 0.44
HTR6 P50406 1/20 0.43
TNF P01375 1/20 0.42
NOD2 Q9HC29 1/20 0.42
NOD1 Q9Y239 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PIK3C2B O00750 3/20 0.41
MAPT P10636 2/20 0.41
PPARG P37231 1/20 0.41
TSHR P16473 2/20 0.40
LMNA P02545 1/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
KMT2A Q03164 1/20 0.40
ALOX5AP P20292 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6490954 0.86 TSHR (0.42) DCTPP1GALR3NR2F2RAB9AL3MBTL1
SCHEMBL6491248 0.80 DCTPP1 (0.38) DCTPP1L3MBTL1MAPTLMNAMEN1
SCHEMBL6168582 0.77 PPARG (0.48) DCTPP1TNFNOD2NOD1PIK3C2B
SCHEMBL6503523 0.77 PDE2A (0.40) DCTPP1MAPTPPARGLMNATP53
SCHEMBL1160090 0.76 ALDH1A1 (0.48) DCTPP1BRD4L3MBTL1PIK3C2BMAPT
SCHEMBL6498083 0.75 DCTPP1 (0.35) DCTPP1GALR3NR2F2RAB9AHTR6
SCHEMBL6489563 0.75 SMN1; SMN2 (0.52) DCTPP1NPC1RAB9APIK3C2BMAPT
SCHEMBL6489339 0.74 LMNA (0.37) DCTPP1L3MBTL1PIK3C2BMAPTPPARG
SCHEMBL6503536 0.74 MCL1 (0.46) DCTPP1PIK3C2BPPARG
SCHEMBL1282459 0.74 DCTPP1 (0.52) DCTPP1PIK3C2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050014812-A1 Benzimidazole compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2005-01-20 US disclosed
WO-2004108686-A2 BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-12-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050014812-A1 Benzimidazole compounds SLC5A1, SLC5A2, G6PD DCTPP1 1534/4885GALR3 4497/4885NR2F2 3661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.