Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.45 |
| ▸ | EPAS1 | Q99814 | 5/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | CLPP | Q16740 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.37 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6488692 | 0.88 | SLC2A1 (0.52) | ARHIF1AEPAS1SLC2A1CLPP | |
| SCHEMBL6489984 | 0.79 | NAMPT (0.55) | SLC2A1CYP3A4CYP2C9CETPMAPKAPK2 | |
| SCHEMBL6491504 | 0.79 | FAAH (0.49) | SLC2A1 | |
| SCHEMBL6487861 | 0.79 | SLC2A1 (0.49) | ARHIF1AEPAS1SLC2A1CLPP | |
| SCHEMBL6498841 | 0.78 | CLPP (0.52) | HIF1AEPAS1SLC2A1CLPP | |
| SCHEMBL6490947 | 0.78 | HIF1A (0.51) | HIF1AEPAS1CYP3A4CYP2C9MAPKAPK2 | |
| SCHEMBL6490911 | 0.76 | HIF1A (0.53) | HIF1AEPAS1SLC2A1CYP3A4CYP2C9 | |
| SCHEMBL6497061 | 0.76 | MAPKAPK2 (0.50) | HIF1AEPAS1MAPKAPK2KCNH2 | |
| SCHEMBL6496541 | 0.76 | MAPT (0.57) | HIF1AEPAS1MAPKAPK2 | |
| SCHEMBL6490805 | 0.75 | HIF1A (0.64) | HIF1AEPAS1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | AR 1317/4885HIF1A 2476/4885EPAS1 1386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.