Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGAV | P06756 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490548 | 1.00 | FFAR1 (0.50) | FFAR1PKMMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL27532652 | 0.86 | F10 (0.45) | FFAR1MTNR1AMTNR1BALDH1A1LMNA | |
| SCHEMBL6176524 | 0.85 | PKM (0.60) | FFAR1PKMALDH1A1LDHAFNTA | |
| SCHEMBL6490642 | 0.84 | MME (0.44) | FFAR1ITGB3ITGAV | |
| SCHEMBL6490651 | 0.84 | MME (0.44) | FFAR1ITGB3ITGAV | |
| SCHEMBL27829876 | 0.80 | ALDH1A1 (0.62) | FFAR1PKMMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL5857867 | 0.79 | GABBR2 (0.50) | FFAR1FNTAFNTBITGB3ITGAV | |
| SCHEMBL7447623 | 0.78 | ALDH1A1 (0.46) | FFAR1ALDH1A1LMNAGAAFNTA | |
| SCHEMBL6491361 | 0.78 | ITGB3 (0.60) | FFAR1PKMGAALDHAFNTA | |
| SCHEMBL6491359 | 0.78 | ITGB3 (0.60) | FFAR1PKMGAALDHAFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | disclosed |
| EP-1218005-B1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2004-12-15 | — | — | EP | disclosed |
| EP-1218005-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-10-09 | — | — | EP | disclosed |
| EP-1218005-A2 | VITRONECTIN RECEPTOR ANTAGONISTS | SmithKline Beecham Corporation (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001017959-A2 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-03-15 | — | — | WO | disclosed |