Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3874969 | 0.79 | MAOA (0.75) | MAOAMAOBGPR3MAPTALDH1A1 | |
| SCHEMBL6489524 | 0.77 | GPR3 (0.50) | GPR3MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3874563 | 0.76 | MAOA (0.57) | MAOAMAOBGPR3MAPTALDH1A1 | |
| Hydrogen Sulfide SCHEMBL29100291 | 0.75 | GPR3 (0.48) | MAOAMAOBGPR3MAPTALDH1A1 | |
| SCHEMBL28076011 | 0.72 | GPR3 (0.45) | MAOAMAOBGPR3MAPTALDH1A1 | |
| SCHEMBL8176419 | 0.71 | HSD17B1 (0.50) | MAOAMAOBMAPTALDH1A1MEN1 | |
| SCHEMBL28075901 | 0.71 | GPR3 (0.43) | MAOAMAOBGPR3MAPTALDH1A1 | |
| SCHEMBL24627993 | 0.70 | MAOA (0.54) | MAOAMAOBGPR3MAPTALDH1A1 | |
| SCHEMBL11030869 | 0.70 | MAOA (1.00) | MAOAMAOBMAPTALDH1A1MEN1 | |
| SCHEMBL28269977 | 0.70 | GPR3 (0.42) | MAOAMAOBGPR3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881850-B2 | Heterocyclically annellated indenochromene derivatives | RODENSTOCK GMBH (DE) | 2005-04-19 | — | — | US | disclosed |
| US-6849202-B2 | COMPOUND HAVING PHENYLACETYLENE STRUCTURE, LIQUID CRYSTAL COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC PRODUCT, OPTICAL OR LIQUID CRYSTAL ELEMENT, DIBENZOTHIOPHENE COMPOUND, INTERMEDIATE, AND PROCESS FOR PRODUCING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-02-01 | — | — | US | disclosed |
| US-20040092743-A1 | Heterocyclically annellated indenochromene derivatives | OPTISCHE WERKE G. RODENSTOCK | 2004-05-13 | — | — | US | disclosed |
| US-6660727-B1 | Photochromic heterocyclically anellated indenochromene compounds | RODENSTOCK GMBH (DE) | 2003-12-09 | — | — | US | disclosed |
| US-20020110650-A1 | Compound having phenylacetylene structure, liquid crystal composition, polymer, optically anisotropic product, optical or liquid crystal element, dibenzothiophene compound, intermediate, and process for producing the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2002-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092743-A1 | Heterocyclically annellated indenochromene derivatives | ALDH1A2, INF2, CYP1B1 | MAOA 1203/4885MAOB 1241/4885GPR3 1289/4885 |
| US-20020110650-A1 | Compound having phenylacetylene structure, liquid crystal composition, polymer, optically anisotropic product, optical or liquid crystal element, dibenzothiophene compound, intermediate, and process for producing the same | CCNT1, NAT1, PEAK1 | MAOA 1823/4885MAOB 2546/4885GPR3 2764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.