Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 7/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 7/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 7/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CFD | P00746 | 2/20 | 0.40 |
| ▸ | F11 | P03951 | 2/20 | 0.40 |
| ▸ | TPSB2 | P20231 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490654 | 1.00 | PTGER1 (0.41) | PTGER1PTGER4PTGER3PTGER2L3MBTL1 | |
| SCHEMBL6502665 | 0.83 | ALOX5 (0.49) | KMT2A | |
| SCHEMBL6490658 | 0.83 | ALOX5 (0.49) | KMT2A | |
| SCHEMBL68571 | 0.71 | L3MBTL1 (0.69) | PTGER1PTGER4PTGER3PTGER2L3MBTL1 | |
| SCHEMBL31757965 | 0.70 | CFD (0.68) | PTGER1PTGER4PTGER3PTGER2L3MBTL1 | |
| SCHEMBL1007508 | 0.70 | CFD (0.68) | PTGER1PTGER4PTGER3PTGER2L3MBTL1 | |
| Bicarbonate SCHEMBL27963003 | 0.70 | HTR1A (0.61) | PTGER1PTGER4PTGER3PTGER2L3MBTL1 | |
| SCHEMBL16109348 | 0.70 | PTGER1 (0.41) | PTGER1KMT2A | |
| SCHEMBL16109350 | 0.70 | PTGER1 (0.41) | PTGER1KMT2A | |
| SCHEMBL16108466 | 0.70 | SIRT2 (0.44) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | disclosed |