Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3278019 | 0.78 | MAPT (0.37) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL27727721 | 0.78 | ALDH1A1 (0.37) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL27733187 | 0.78 | TLR4 (0.45) | ALDH1A1LMNAALOX5MEN1KMT2A | |
| SCHEMBL9650669 | 0.77 | — | — | |
| SCHEMBL9650877 | 0.75 | CETP (0.35) | MEN1KMT2A | |
| SCHEMBL29192714 | 0.73 | MAOB (0.49) | ALOX5MEN1KMT2A | |
| SCHEMBL445246 | 0.73 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7115834 | 0.72 | ALOX5 (0.51) | ALDH1A1ALOX5MEN1KMT2A | |
| SCHEMBL9650828 | 0.72 | MEN1 (0.38) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL3296222 | 0.69 | CRHBP (0.49) | ALDH1A1LMNAALOX5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908996-B2 | Compounds and method for preparing 3-methylcephams | IMPERIAL COLLEGE OF LONDON (GB) | 2005-06-21 | — | — | US | disclosed |
| US-20040106790-A1 | Novel compounds and method for preparing 3-methylcephams | COOPER CONSULTING | 2004-06-03 | — | — | US | disclosed |
| US-6683176-B2 | FOR USE IN PRODUCING AMINO ACID DERIVATIVE ANTIBIOTICS | COOPER CONSULTING | 2004-01-27 | — | — | US | disclosed |
| EP-1183262-A4 | INTERMEDIATES FOR AND SYNTHESIS OF 3-METHYLENE CEPHAMS | COOPER CONSULTING INC (US) | 2003-04-09 | — | — | EP | disclosed |
| US-20030036650-A1 | Intermediates for and synthesis of 3-methylene cephams | IMPERIAL COLLEGE OF LONDON (GB) | 2003-02-20 | — | — | US | disclosed |
| EP-1183262-A1 | INTERMEDIATES FOR AND SYNTHESIS OF 3-METHYLENE CEPHAMS | Cooper Consulting Inc. (US) | 2002-03-06 | — | — | EP | disclosed |
| WO-2001060828-A1 | INTERMEDIATES FOR AND SYNTHESIS OF 3-METHYLENE CEPHAMS | COOPER CONSULTING INC. (US) | 2001-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030036650-A1 | Intermediates for and synthesis of 3-methylene cephams | LSS, DHPS, COASY | ALDH1A1 1396/4885LMNA 1384/4885ALOX5 1020/4885 |
| US-20040106790-A1 | Novel compounds and method for preparing 3-methylcephams | DHPS, FDPS, COASY | ALDH1A1 2083/4885LMNA 2777/4885ALOX5 1673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.