Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL31415921 | 0.95 | — | — | |
| SCHEMBL1866819 | 0.95 | — | — | |
| Potassium Ion SCHEMBL11902986 | 0.85 | KDM4E (0.34) | — | |
| Lithium Ion SCHEMBL28706066 | 0.84 | — | — | |
| Potassium Ion SCHEMBL18008320 | 0.83 | KDM4E (0.33) | — | |
| Potassium Ion SCHEMBL18008542 | 0.81 | CA2 (0.33) | — | |
| Potassium Ion SCHEMBL18007956 | 0.81 | CA2 (0.33) | — | |
| Potassium Ion SCHEMBL18008975 | 0.81 | CA2 (0.33) | — | |
| Potassium Ion SCHEMBL18007966 | 0.81 | CA2 (0.33) | — | |
| Potassium Ion SCHEMBL18008056 | 0.81 | CA2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2877477-B1 | PROCESS FOR THE PREPARATION OF PHOSPHONIUM SULFONATES | MITENI SPA (IT) | 2016-12-07 | — | — | EP | disclosed |
| US-8735603-B2 | N-substituted pyrrolidonium ionic liquids with expanded linker | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-05-27 | — | — | US | disclosed |
| EP-2358672-B1 | N-SUBSTITUTED PYRROLIDONIUM IONIC LIQUIDS WITH EXPANDED LINKER | DU PONT (US) | 2013-04-17 | — | — | EP | disclosed |
| US-8350056-B2 | Functionalized N-substituted pyrrolidonium ionic liquids | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-08 | — | — | US | disclosed |
| EP-1984441-B1 | COATING PROCESS FOR THERMOPLASTICS | DU PONT (US) | 2012-08-15 | — | — | EP | disclosed |
| US-20120130088-A1 | N-Substituted Pyrrolidonium Ionic Liquids with Expanded Linker | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-05-24 | — | — | US | disclosed |
| US-8119818-B2 | Functionalized N-substituted pyrrolidonium ionic liquids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-02-21 | — | — | US | disclosed |
| EP-2370404-A2 | FUNCTIONALIZED N-SUBSTITUTED PYRROLIDONIUM IONIC LIQUIDS | E. I. du Pont de Nemours and Company (US) | 2011-10-05 | — | — | EP | disclosed |
| EP-2358672-A1 | N-SUBSTITUTED PYRROLIDONIUM IONIC LIQUIDS WITH EXPANDED LINKER | E. I. du Pont de Nemours and Company (US) | 2011-08-24 | — | — | EP | disclosed |
| US-20110137048-A1 | FUNCTIONALIZED N-SUBSTITUTED PYRROLIDONIUM IONIC LIQUIDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-06-09 | — | — | US | disclosed |
| WO-2010065841-A1 | N-SUBSTITUTED PYRROLIDONIUM IONIC LIQUIDS WITH EXPANDED LINKER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-10 | — | — | WO | disclosed |
| US-20100143992-A1 | Process for Fermentive Preparation of Alcohols and Recovery of Product | E. I DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-10 | — | — | US | disclosed |
| US-20100144000-A1 | PROCESS FOR FERMENTIVE PREPARATION FO ALCOHOLS AND RECOVERY OF PRODUCT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-10 | — | — | US | disclosed |
| US-20100143993-A1 | PROCESS FOR FERMENTIVE PREPARATIONFOR ALCOLHOLS AND RECOVERY OF PRODUCT | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-10 | — | — | US | disclosed |
| US-20100143999-A1 | PROCESS FOR FERMENTIVE PREPARATION OF ALCOHOLS AND RECOVERY OF PRODUCT | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-10 | — | — | US | disclosed |
| WO-2010065606-A2 | PROCESS FOR FERMENTIVE PREPARATION OF ALCOHOLS AND RECOVERY OF PRODUCT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-10 | — | — | WO | disclosed |
| WO-2010065833-A2 | FUNCTIONALIZED N-SUBSTITUTED PYRROLIDONIUM IONIC LIQUIDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-10 | — | — | WO | disclosed |
| US-20100143994-A1 | PROCESS FOR FERMENTIVE PREPARATION OF ALCOHOLS AND RECOVERY OF PRODUCT | E. I. DU PONT DE MEMOURS AND COMPANY | 2010-06-10 | — | — | US | disclosed |
| EP-1984441-A1 | COATING PROCESS FOR THERMOPLASTICS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007089585-A1 | COATING PROCESS FOR THERMOPLASTICS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-08-09 | — | — | WO | disclosed |