Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.59 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 8/20 | 0.54 |
| ▸ | CTSK | P43235 | 7/20 | 0.54 |
| ▸ | CTSB | P07858 | 4/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2352344 | 1.00 | KLK5 (0.59) | KLK5NLRP3CTSSCTSKCTSB | |
| SCHEMBL30765043 | 1.00 | KLK5 (0.59) | KLK5NLRP3CTSSCTSKCTSB | |
| SCHEMBL2352336 | 1.00 | KLK5 (0.59) | KLK5NLRP3CTSSCTSKCTSB | |
| SCHEMBL29543144 | 1.00 | KLK5 (0.59) | KLK5NLRP3CTSSCTSKCTSB | |
| SCHEMBL15856094 | 0.94 | CTSS (0.55) | KLK5NLRP3CTSSCTSKCTSB | |
| SCHEMBL15856124 | 0.94 | CTSS (0.55) | KLK5NLRP3CTSSCTSKCTSB | |
| SCHEMBL12643835 | 0.90 | CTSS (0.52) | KLK5NLRP3CTSSCTSKCTSB | |
| SCHEMBL16459766 | 0.89 | CTSS (0.51) | KLK5NLRP3CTSSCTSKCTSB | |
| SCHEMBL20905929 | 0.89 | CTSS (0.56) | KLK5CTSSCTSKCTSBCTSL | |
| SCHEMBL14576685 | 0.89 | CTSS (0.56) | KLK5CTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067665-A1 | SMALL MOLECULES FOR BORON NEUTRON CAPTURE THERAPY | AVIKO RADIOPHARMACEUTICALS LLC (US) | 2024-02-29 | — | — | US | disclosed |
| US-20050043358-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-02-24 | — | — | US | disclosed |
| US-20020143034-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2002-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143034-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB1, ADRB2, ADRB3 | KLK5 4614/4885NLRP3 3635/4885CTSS 4294/4885 |
| US-20050043358-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB2, ADRB1, ADRB3 | KLK5 4605/4885NLRP3 3646/4885CTSS 4072/4885 |
| US-20240067665-A1 | SMALL MOLECULES FOR BORON NEUTRON CAPTURE THERAPY | NME2, BTD, BLVRB | KLK5 2119/4885NLRP3 4825/4885CTSS 1784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.