Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.47 |
| ▸ | ITGAV | P06756 | 3/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6493595 | 1.00 | ITGB3 (0.47) | ITGB3ITGAVITGB1ITGB6KCNA5 | |
| SCHEMBL6179138 | 0.85 | GABBR2 (0.56) | KCNH2AKR1B1GABBR2GABBR1LMNA | |
| SCHEMBL6179146 | 0.85 | GABBR2 (0.56) | KCNH2AKR1B1GABBR2GABBR1LMNA | |
| SCHEMBL5856512 | 0.82 | TBXAS1 (0.53) | ITGB3ITGAVITGB1ITGB6TBXAS1 | |
| SCHEMBL6493601 | 0.80 | ITGB3 (0.56) | ITGB3ITGAVITGB1ITGB6TBXAS1 | |
| SCHEMBL6491322 | 0.80 | ITGB3 (0.56) | ITGB3ITGAVITGB1ITGB6TBXAS1 | |
| SCHEMBL22775935 | 0.77 | TBXAS1 (0.48) | ITGB3ITGAVITGB1ITGB6TBXAS1 | |
| SCHEMBL11990053 | 0.75 | TBXAS1 (0.63) | ITGB3ITGAVKCNA5TBXAS1SMN1; SMN2 | |
| SCHEMBL25151973 | 0.74 | ITGB3 (0.46) | ITGB3ITGAVITGB1ITGB6KCNA5 | |
| SCHEMBL25152268 | 0.74 | ITGB3 (0.46) | ITGB3ITGAVITGB1ITGB6KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | disclosed |