SCHEMBL649415

SCHEMBL649415

COc1ccccc1-c1nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.47
HSD17B10 Q99714 8/20 0.47
SMN1; SMN2 Q16637 8/20 0.47
TSHR P16473 7/20 0.47
TP53 P04637 6/20 0.47
CYP1A2 P05177 5/20 0.47
CYP3A4 P08684 5/20 0.47
CYP2D6 P10635 5/20 0.47
KDM4E B2RXH2 5/20 0.47
LMNA P02545 4/20 0.47
USP2 O75604 2/20 0.47
MAPK1 P28482 2/20 0.47
CYP2C19 P33261 2/20 0.47
ALOX15 P16050 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
RAB9A P51151 5/20 0.46
NPC1 O15118 4/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HPGD P15428 2/20 0.44
ADORA3 P0DMS8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29353355 1.00 ALDH1A1 (0.47) ALDH1A1HSD17B10SMN1; SMN2TSHRTP53
SCHEMBL6330998 0.85 ADORA2A (0.47) ALDH1A1HSD17B10SMN1; SMN2TP53KDM4E
SCHEMBL393466 0.85 CYP1A2 (0.40) ALDH1A1HSD17B10SMN1; SMN2TSHRTP53
SCHEMBL544836 0.84 ALDH1A1 (0.49) ALDH1A1HSD17B10SMN1; SMN2TSHRTP53
SCHEMBL3190486 0.82 NPSR1 (0.44) ALDH1A1HSD17B10SMN1; SMN2TSHRKDM4E
SCHEMBL29350011 0.82 IDO1 (0.42) ALDH1A1HSD17B10SMN1; SMN2TSHRTP53
SCHEMBL62367 0.82 IDO1 (0.42) ALDH1A1HSD17B10SMN1; SMN2TSHRTP53
SCHEMBL10344664 0.82 ALDH1A1 (0.41) ALDH1A1HSD17B10SMN1; SMN2TSHRTP53
SCHEMBL16928136 0.81 CYP1A2 (0.56) ALDH1A1HSD17B10TSHRTP53CYP1A2
SCHEMBL23066466 0.81 ALDH1A1 (0.61) ALDH1A1HSD17B10SMN1; SMN2TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0324242-A2 Colored foamlike pressure-sensitive adhesive tape MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-07-19 EP claimed
US-12583973-B2 Polyimide-based polymer, positive photosensitive resin composition, negative photosensitive resin composition, patterning method, method for forming cured film, interlayer insulating film, surface protective film, and electronic component SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-03-24 US disclosed
US-12503551-B2 Fluorine-containing isocyanul compound DAIKIN INDUSTRIES, LTD. (JP) 2025-12-23 US disclosed
EP-4617775-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN FILM, PHOTOSENSITIVE DRY FILM, PATTERN FORMING METHOD, AND LIGHT-EMITTING ELEMENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-09-17 EP disclosed
EP-4600743-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN MEMBRANE, PHOTOSENSITIVE DRY FILM, PATTERN FORMATION METHOD, AND LIGHT-EMITTING ELEMENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-08-13 EP disclosed
EP-4600741-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN COATING, PHOTOSENSITIVE DRY FILM, PATTERN FORMING METHOD, AND LIGHT-EMITTING ELEMENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-08-13 EP disclosed
US-20250251665-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN FILM, PHOTOSENSITIVE DRY FILM, AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-08-07 US disclosed
US-12216405-B2 Photosensitive resin composition, photosensitive resin film, photosensitive dry film, patterning process, and light emitting device SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-02-04 US disclosed
EP-4257631-B1 NOVEL COMPOUND HAVING ISOCYANURIC SKELETON AND COMPOSITION IN WHICH SAID COMPOUND IS INCLUDED DAIKIN IND LTD (JP) 2024-12-11 EP disclosed
WO-2024202643-A1 METHOD FOR PRODUCING WIRING BOARD 味の素株式会社 2024-10-03 WO disclosed
US-5679495-A TERPOLYMER PHOTORESIST CONTAINING VINYLPHENOL DERIVATIVE, TERT-BUTYL (METH)ACRYLATE, AND A UNIT TO REDUCE ALKALINE SOLUBILITY; DRY ETCH RESISTANCE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-10-21 US disclosed
EP-0789278-A2 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-08-13 EP disclosed
EP-0775941-A1 Radiation sensitive composition for color filters JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-05-28 EP disclosed
US-5629135-A ALKALI-SOLUBLE RESIN, CROSSLINKER, PHOTOACID GENERATOR, SOLVENT JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-05-13 US disclosed
EP-0660187-B1 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1997-03-05 EP disclosed
US-5556734-A RESISTS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-09-17 US disclosed
EP-0726500-A1 Chemically amplified, radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-08-14 EP disclosed
EP-0660187-A1 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1995-06-28 EP disclosed
EP-0634696-A1 Chemically amplified resist composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1995-01-18 EP disclosed
EP-0554005-A1 Photopolymerisable components of radiation-sensitive compositions Du Pont (UK) Limited (GB) 1993-08-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12503551-B2 Fluorine-containing isocyanul compound AFF1, FLI1, RIF1 ALDH1A1 572/4885HSD17B10 2411/4885SMN1; SMN2 2071/4885
US-12583973-B2 Polyimide-based polymer, positive photosensitive resin composition, negative photosensitive resin composition, patterning method, method for forming cured film, interlayer insulating film, surface protective film, and electronic component PRDM9, ARCN1, PUF60 ALDH1A1 3281/4885HSD17B10 4119/4885SMN1; SMN2 2618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.